{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Genotypic Technology"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA349053"],"scientific_name":["Escherichia coli"],"long_description":["To achieve extreme manganese stress, we used DmntP E. coli strain. We identified the pathways that are altered under manganese stress. Mainly, manganese altered the metabolism of iron in the cell. Therefore, we have shown that iron supplementation mitigates manganese toxicity. Overall, our data explains the basis of manganism in higher organisms. Overall design: Escherichia coli were grown in LB, LB + manganese, or LB + manganese + iron."],"tag":["pathogen:priority","pathogen:bacterium","pathogen","xref:PubMed:28928443"],"classification":["bacteria"],"repository":["ENA"],"name_synonyms":["Alkalescens-Dispar Group, Enteroaggregative Escherichia coli, Eschericia coli, Diffusely Adherent Escherichia coli, Bacterium coli, Escherichia/Shigella coli, Bacterium coli commune, Enteroinvasive E. coli, Diffusely Adherent E. coli, Bacillus coli, Escherchia coli, E coli, bacterium E3, Enteroinvasive Escherichia coli, Enterococcus coli, EAggEC, Enteroaggregative E. coli, E. coli."],"description_synonyms":["margin of safety, toxic potential."],"additional_accession":[]},"is_claimable":false,"name":"Escherichia coli","description":"Decoding the global transcriptomic profile under extreme manganese toxicity","dates":{"last_updated":"2025-09-24","first_public":"2017-11-03"},"accession":"PRJNA349053","cross_references":{"GEO":["GSE88906"],"taxon":["562"],"PubMed":["28928443"]}}