{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Internal Medicine, Toho University"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA358510"],"scientific_name":["Homo sapiens"],"tag":["xref:PubMed:29404483"],"long_description":["Among all the evaluated factors, only adipose tissue insulin sensitivity (assessed by clamped % suppression of serum free fatty acid), serum concentration of high molecular weight adiponectin, and plasma concentration of TCA cycle metabolites such as citric acid and cis-aconitic acid (assessed by metabolome analysis), associated significantly and positively with hepatic insulin sensitivity in NAFLD. Overall design: We analyzed the data to identify factors associated with preserved hepatic insulin sensitivity despite of hepatic steatosis. The 26 NAFLD patients with intrahepatic lipid content of >5% were divided into three groups according to the level of hepatic insulin sensitivity, as assessed by clamped % suppression of endogenous glucose production. Then, all the evaluated factors were compared between the hepatic insulin sensitive and resistant patients with comparable hepatic steatosis (n=9 vs 8, respectively)."],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Homo sapiens","description":"Identify factors associated with preserved hepatic insulin sensitivity despite of hepatic steatosis.","dates":{"last_updated":"2025-09-24","first_public":"2017-04-19"},"accession":"PRJNA358510","cross_references":{"GEO":["GSE92746"],"taxon":["9606"],"PubMed":["29404483"]}}