{"database":"ENA","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Fastqsanger.gz":["ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR533/007/SRR5331877/SRR5331877.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR533/008/SRR5331878/SRR5331878.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR533/001/SRR5331881/SRR5331881.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR533/000/SRR5331880/SRR5331880.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR533/009/SRR5331879/SRR5331879.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR533/002/SRR5331882/SRR5331882.fastq.gz"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Bresnick lab, Cell and Regenerative Biology, University of Wisconsin Madison"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA378680"],"scientific_name":["Mus musculus"],"long_description":["Gene expression profiles of sorted erythroid precursors from E14.5 wild-type (WT) and -77 enhancer knockout (-77-/-) mouse fetal liver were generated by next generation sequencing, in triplicate, using Illumina Hiseq2500 (1X50). We showed that the Gata2 -77 enhancer generated the vital erythroid precursor Burst Forming Unit-Erythroid by two mechanisms, GATA-1 upregulation to establish the erythroid transcriptome and GATA-2-dependent, GATA-1-independent transcriptional regulation. Overall design: Erythroid precursor gene expression profiles of E14.5 mouse -77+/+ and -77-/- mouse fetal livers were generated by next generation sequencing, in triplicate, using Illumina Hiseq2500 (1X50)."],"tag":["xref:PubMed:28930689"],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Mus musculus","description":"Next Generation sequencing and quantitative transcriptomic analysis in -77+/+ and -77-/- erythroid precursors","dates":{"last_updated":"2025-09-24","first_public":"2017-09-20"},"accession":"PRJNA378680","cross_references":{"GEO":["GSE96059"],"taxon":["10090"],"PubMed":["28930689"]}}