ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR537/001/SRR5376221/SRR5376221_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR537/004/SRR5376224/SRR5376224_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR537/002/SRR5376222/SRR5376222_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR537/000/SRR5376220/SRR5376220_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR537/003/SRR5376223/SRR5376223_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR537/009/SRR5376219/SRR5376219_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR537/009/SRR5376219/SRR5376219_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR537/001/SRR5376221/SRR5376221_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR537/004/SRR5376224/SRR5376224_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR537/002/SRR5376222/SRR5376222_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR537/000/SRR5376220/SRR5376220_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR537/003/SRR5376223/SRR5376223_2.fastq.gzprimaryOK200GenomicsNodwell Lab, Biochemistry, University of Torontohttps://www.ebi.ac.uk/ena/browser/view/PRJNA380398Staphylococcus aureusActinorhodin is a blue-pigmented, redox-active pigmented secondary metabolite that is produced by the bacterium Streptomyces coelicolor. Although actinorhodin has been used as a model compound for studying secondary metabolism, its mechanism is not well understood. In this work, we have conducted a comprehensive chemical genetic investigation of actinorhodin’s antibacterial effect on target organisms. Overall design: Transcriptome profiles of actinorhodin-, H2O2-, and dioxane-treated Staphylococcus aureus were generated in duplicate using Illumina MiSeq platform.pathogen:prioritypathogen:bacteriumxref:PubMed:28906045pathogenbacteriaENAfalseStaphylococcus aureusInvestigation of the Molecular Action of Actinorhodin2025-09-242017-09-23PRJNA380398GSE97007128028906045