ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR545/004/SRR5459184/SRR5459184_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR545/003/SRR5459183/SRR5459183_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR545/002/SRR5459182/SRR5459182_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR545/005/SRR5459185/SRR5459185_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR545/005/SRR5459185/SRR5459185_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR545/002/SRR5459182/SRR5459182_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR545/004/SRR5459184/SRR5459184_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR545/003/SRR5459183/SRR5459183_1.fastq.gzprimaryOK200GenomicsDeqiang Sun, CEDP, Texas A&M U Health Science Centerhttps://www.ebi.ac.uk/ena/browser/view/PRJNA383581Homo sapiensxref:PubMed:29394393We generated 5hmC, WGBS and RNAseq of the cells in 5 stages during hES-to-pancreatic endoderm cell differantiation, and investigated the 5hmC correlation with 4 histones (H3K4me1, H3K4me3, H3K27ac and H3K27me3) during this process. Our results showed that 5hmC is dynamically correlate with enhancers' activities. Overall design: Purpose: Determine the roles of 5hmC during hES to pancreatic endoderm cell differentiation process. The whole genome bisulfite sequencing, CMS-IP, ATAC-seq and RNAseq for the 5 stages (ES,DE,GT,FG,PE) have been sequenced.ENAfalseHomo sapiens5hmC dynamically correlated with enhancer's activities during hES-to-Pancreatic endoderm cell differentiation (Bisulfite-Seq)2025-09-242018-04-20PRJNA383581GSE97991960629394393