<HashMap><database>ENA</database><file_versions><headers><Content-Type>application/xml</Content-Type></headers><body><files><Fastqsanger.gz>ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR545/004/SRR5459174/SRR5459174.fastq.gz</Fastqsanger.gz><Fastqsanger.gz>ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR545/005/SRR5459175/SRR5459175.fastq.gz</Fastqsanger.gz><Fastqsanger.gz>ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR545/006/SRR5459176/SRR5459176.fastq.gz</Fastqsanger.gz><Fastqsanger.gz>ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR545/009/SRR5459179/SRR5459179.fastq.gz</Fastqsanger.gz><Fastqsanger.gz>ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR545/007/SRR5459177/SRR5459177.fastq.gz</Fastqsanger.gz><Fastqsanger.gz>ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR545/001/SRR5459181/SRR5459181.fastq.gz</Fastqsanger.gz><Fastqsanger.gz>ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR545/000/SRR5459180/SRR5459180.fastq.gz</Fastqsanger.gz><Fastqsanger.gz>ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR545/008/SRR5459178/SRR5459178.fastq.gz</Fastqsanger.gz></files><type>primary</type></body><statusCode>OK</statusCode><statusCodeValue>200</statusCodeValue></file_versions><scores/><additional><omics_type>Genomics</omics_type><center_name>Jia Li Lab, CEDP, Texas A&amp;M U Health Science Center</center_name><full_dataset_link>https://www.ebi.ac.uk/ena/browser/view/PRJNA383582</full_dataset_link><scientific_name>Homo sapiens</scientific_name><long_description>We generated 5hmC, WGBS and RNAseq of the cells in 5 stages during hES-to-pancreatic endoderm cell differantiation, and investigated the 5hmC correlation with 4 histones (H3K4me1, H3K4me3, H3K27ac and H3K27me3) during this process. Our results showed that 5hmC is dynamically correlate with enhancers' activities. Overall design: Purpose: Determine the roles of 5hmC during hES to pancreatic endoderm cell differentiation process. The whole genome bisulfite sequencing, CMS-IP, ATAC-seq and RNAseq for the 5 stages (ES,DE,GT,FG,PE) have been sequenced.</long_description><tag>xref:PubMed:29394393</tag><repository>ENA</repository></additional><is_claimable>false</is_claimable><name>Homo sapiens</name><description>5hmC dynamically correlated with enhancer's activities during hES-to-Pancreatic endoderm cell differentiation (RNA-Seq)</description><dates><last_updated>2025-09-24</last_updated><first_public>2018-04-20</first_public></dates><accession>PRJNA383582</accession><cross_references><GEO>GSE97990</GEO><taxon>9606</taxon><PubMed>29394393</PubMed></cross_references></HashMap>