{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Semmelweis University"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA384020"],"scientific_name":["Homo sapiens"],"long_description":["Transcriptional profiling of human umbilical vein endothelial cells, treated with MASP-1, thrombin, LPS, histamine, TNFalpha, MASP-1+SB203580 (p38-MAPK inhibitor) or MASP-1+Bay-117082 (NFKB inhibitor). Goal was to determine the effect of MASP-1 on HUVECs, to compare this with the effect of other endothelial cell activators and to determine the MASP-1 induced signalling pathways. Overall design: Two-color microarray experiment, with several different treatments. 13 samples were analyzed. 2h MASP-1 treatment: 4 biological replicates TNFalpha treatment: 2 replicates 1h MASP-1, 6h MASP-1, LPS, histamine, thrombin, SB203580, Bay-117082 treatment: 1-1 replicate"],"tag":["xref:PubMed:31130964","xref:PubMed:28874747","xref:PubMed:38612857"],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Homo sapiens","description":"Transcriptome analysis of inflammation-related gene expression in endothelial cells activated by complement MASP-1","dates":{"last_updated":"2025-09-24","first_public":"2017-09-16"},"accession":"PRJNA384020","cross_references":{"GEO":["GSE98114"],"taxon":["9606"],"PubMed":["31130964","38612857","28874747"]}}