ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/001/SRR5629711/SRR5629711_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/008/SRR5629708/SRR5629708_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/007/SRR5629707/SRR5629707_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/002/SRR5629712/SRR5629712_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/003/SRR5629703/SRR5629703.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/000/SRR5629710/SRR5629710_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/005/SRR5629705/SRR5629705_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/009/SRR5629709/SRR5629709_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/007/SRR5629707/SRR5629707.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/006/SRR5629706/SRR5629706_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/001/SRR5629711/SRR5629711_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/009/SRR5629709/SRR5629709.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/002/SRR5629712/SRR5629712_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/000/SRR5629710/SRR5629710_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/002/SRR5629712/SRR5629712.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/006/SRR5629706/SRR5629706.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/003/SRR5629703/SRR5629703_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/005/SRR5629705/SRR5629705.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/005/SRR5629705/SRR5629705_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/006/SRR5629706/SRR5629706_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/002/SRR5629702/SRR5629702_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/001/SRR5629711/SRR5629711.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/002/SRR5629702/SRR5629702.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/004/SRR5629704/SRR5629704_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/004/SRR5629704/SRR5629704.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/000/SRR5629710/SRR5629710.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/009/SRR5629709/SRR5629709_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/008/SRR5629708/SRR5629708.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/007/SRR5629707/SRR5629707_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/004/SRR5629704/SRR5629704_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/003/SRR5629703/SRR5629703_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/002/SRR5629702/SRR5629702_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR562/008/SRR5629708/SRR5629708_2.fastq.gzprimaryOK200Genomicsst jude children's hospitalhttps://www.ebi.ac.uk/ena/browser/view/PRJNA388487Mus musculusDe novo DNA methylation establishes T cell exhaustion and inhibits PD-1 blockade-mediated T-cell rejuvenation. Overall design: Mouse antigen-specific CD8 T cells were sorted from spleens of WT and Dnmt3a cKO mice during chronic LCMV infection on day 8 and day 35 post-infection for whole genome bisulfite sequencing [WGBS] analyses. Mouse antigen-specific CD8 T cells were sorted from spleens of WT mice during chronic LCMV infection after mock or PD-L1 blockade treatment for WGBS analyses. Mouse antigen-specific CD8 T cells were sorted from WT mice during acute LCMV infection on day 35 post-infection for WGBS analysis.xref:PubMed:28648661ENAfalseMus musculusDe novo epigenetic programs inhibit PD-1 blockade-mediated T-cell rejuvenation [WGBS]2025-09-242017-07-02PRJNA388487GSE994501009028648661