{"database":"ENA","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Fastqsanger.gz":["ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR613/003/SRR6130313/SRR6130313.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR613/005/SRR6130315/SRR6130315.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR613/000/SRR6130310/SRR6130310.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/014/SRR16926214/SRR16926214.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR169/015/SRR16926215/SRR16926215.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR613/004/SRR6130314/SRR6130314.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR613/009/SRR6130319/SRR6130319.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR613/000/SRR6130320/SRR6130320.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR613/006/SRR6130316/SRR6130316.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR613/001/SRR6130311/SRR6130311.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR613/002/SRR6130312/SRR6130312.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR613/009/SRR6130309/SRR6130309.fastq.gz"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Royal college of Surgeons in Ireland"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA413139"],"scientific_name":["Rattus norvegicus"],"long_description":["To investigate molecular network mediated by miR-143, we analyzed the transcriptome profile of retinas isolated from neonatal pups subjected to either normoxia or oxygen-induced retinopathy (OIR) for 14 days (P14) receiving an intravitreal injection of either scrambled miRNAs (control) or miR-143 mimics. Total RNAs were isolated from the retinas and subjected to RNA-Seq. Analysis of RNA-Seq data identified 2064 genes with altered levels between OIR rats and shame rats receiving scrambled RNAs (adjusted p<0.05). Overall design: Four groups of samples were analysed: 1) OIR with scrambled RNA (n=3) 2) OIR with miR-143 mimic (n=3) 3) Sham with scrambled RNA (n=3) 4) Sham with miR-143 mimic (n=3)"],"tag":["xref:PubMed:34797904"],"repository":["ENA"],"description_synonyms":["HH, Ribonucleic, Ischemias, Transcriptome Profile, stRNA, bar, Gene Expression Profile, Ischemia, Gene, Profiles, IDOL, Hh, Small, Readability, anon-WO0134654.19, DmelCG4637, Roles, Transcriptome Profiles., Gene Products, Concepts, retinopathy, Mir, MIR, Non Polyadenylated, RNA Gene Products, Miranda, Ischemia (disorder), Small Temporal, MONDOA, Mrt, Profile, mir, miRNA, Primary miRNA, pri-miRNA, INSDC_feature:ncRNA, Signatures, Ischaemia, Non-Polyadenylated RNA, Myosin regulatory light chain-interacting protein, retina eye disease, Expression Signature, bar-3, Role Concepts, Transcriptomes, bHLHe36, Idol, pre miRNA, 9430057C20Rik, RNA, l(3)hh, Transcriptome, Myosin regulatory light chain interacting protein, ribose nucleic acid, 6.3.2.-, Expression Profiles, ribonucleic acids, Small Temporal RNA, RNS, Primary, CG4637, Concept, CG12249, AW228700, Gene Expression, retinal disease, Role Concept, Micro RNA, yeast nucleic acid, Ribonukleinsaeure, Expression Signatures, bar3, Gene Expression Signatures, Role, pentosenucleic acids, NOS, DmelCG12249, retinal disorder, Ribonucleic acids, Gene Expression Signature, pre-miRNA, Expression Profile, pri miRNA, ribonucleic acid, Acid, miRNAs, l(3)neo56, l(3)neo57, Micro, Temporal RNA, Non Polyadenylated RNA, Mira, eye disease of retina, Non-Polyadenylated, Primary MicroRNA, Inducible degrader of the LDL-receptor, Ribonucleic Acid, Understanding, anon-WO0182946.19, Gene Expression Profiles, MIRA, ischemia, MicroRNA, Signature, hg"],"name_synonyms":["HH, Ribonucleic, Ischemias, Transcriptome Profile, stRNA, bar, Gene Expression Profile, Ischemia, Gene, Profiles, IDOL, Hh, Small, Readability, anon-WO0134654.19, DmelCG4637, Roles, Transcriptome Profiles., Gene Products, Concepts, retinopathy, Mir, MIR, Non Polyadenylated, RNA Gene Products, Miranda, Ischemia (disorder), Small Temporal, MONDOA, Mrt, Profile, mir, miRNA, Primary miRNA, pri-miRNA, INSDC_feature:ncRNA, Signatures, Ischaemia, Non-Polyadenylated RNA, Myosin regulatory light chain-interacting protein, retina eye disease, Expression Signature, bar-3, Role Concepts, Transcriptomes, bHLHe36, Idol, pre miRNA, 9430057C20Rik, RNA, l(3)hh, Transcriptome, Myosin regulatory light chain interacting protein, ribose nucleic acid, 6.3.2.-, Expression Profiles, ribonucleic acids, Small Temporal RNA, RNS, Primary, CG4637, Concept, CG12249, AW228700, Gene Expression, retinal disease, Role Concept, Micro RNA, yeast nucleic acid, Ribonukleinsaeure, Expression Signatures, bar3, Gene Expression Signatures, Role, pentosenucleic acids, NOS, DmelCG12249, retinal disorder, Ribonucleic acids, Gene Expression Signature, pre-miRNA, Expression Profile, pri miRNA, ribonucleic acid, Acid, miRNAs, l(3)neo56, l(3)neo57, Micro, Temporal RNA, Non Polyadenylated RNA, Mira, eye disease of retina, Non-Polyadenylated, Primary MicroRNA, Inducible degrader of the LDL-receptor, Ribonucleic Acid, Understanding, anon-WO0182946.19, Gene Expression Profiles, MIRA, ischemia, MicroRNA, Signature, hg"],"additional_accession":[]},"is_claimable":false,"name":"Understanding the role of miRNA-143 (miR-143) in ischemia-induced retinopathy via RNA transcriptome profiling","description":"Understanding the role of miRNA-143 (miR-143) in ischemia-induced retinopathy via RNA transcriptome profiling","dates":{"last_updated":"2025-09-24","first_public":"2021-10-03"},"accession":"PRJNA413139","cross_references":{"GEO":["GSE104588"],"taxon":["10116"],"PubMed":["34797904"]}}