ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/007/SRR6815457/SRR6815457.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/005/SRR6815455/SRR6815455_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/003/SRR6815463/SRR6815463.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/003/SRR6815453/SRR6815453_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/007/SRR6815457/SRR6815457_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/008/SRR6815448/SRR6815448_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/002/SRR6815462/SRR6815462.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/001/SRR6815451/SRR6815451_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/006/SRR6815456/SRR6815456.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/009/SRR6815459/SRR6815459_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/005/SRR6815455/SRR6815455_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/003/SRR6815453/SRR6815453_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/000/SRR6815460/SRR6815460_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/000/SRR6815450/SRR6815450.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/001/SRR6815461/SRR6815461_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/003/SRR6815463/SRR6815463_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/005/SRR6815455/SRR6815455.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/008/SRR6815448/SRR6815448_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/006/SRR6815456/SRR6815456_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/008/SRR6815458/SRR6815458_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/000/SRR6815460/SRR6815460_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/007/SRR6815447/SRR6815447_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/000/SRR6815450/SRR6815450_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/004/SRR6815464/SRR6815464.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/002/SRR6815462/SRR6815462_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/002/SRR6815452/SRR6815452_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/004/SRR6815454/SRR6815454_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/004/SRR6815464/SRR6815464_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/008/SRR6815448/SRR6815448.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/009/SRR6815449/SRR6815449_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/006/SRR6815456/SRR6815456_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/000/SRR6815450/SRR6815450_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/004/SRR6815454/SRR6815454.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/000/SRR6815460/SRR6815460.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/002/SRR6815452/SRR6815452_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/008/SRR6815458/SRR6815458_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/003/SRR6815453/SRR6815453.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/007/SRR6815447/SRR6815447.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/004/SRR6815454/SRR6815454_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/002/SRR6815462/SRR6815462_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/007/SRR6815447/SRR6815447_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/007/SRR6815457/SRR6815457_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/009/SRR6815459/SRR6815459_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/009/SRR6815449/SRR6815449_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/009/SRR6815449/SRR6815449.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/002/SRR6815452/SRR6815452.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/001/SRR6815451/SRR6815451.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/004/SRR6815464/SRR6815464_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/009/SRR6815459/SRR6815459.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/001/SRR6815461/SRR6815461_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/001/SRR6815451/SRR6815451_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/008/SRR6815458/SRR6815458.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/001/SRR6815461/SRR6815461.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR681/003/SRR6815463/SRR6815463_1.fastq.gzprimaryOK200GenomicsDr. Rongfu Wang's lab, Center for Inflammation and Epigenetics, Houston Methodist Research Institutehttps://www.ebi.ac.uk/ena/browser/view/PRJNA437320Mus musculusOur study represents the first detailed analysis of WT vs Beclin 2 KO cell/tissue transcriptomes, with biologic replicates, generated by RNA-seq technology. RNA-seq based transcriptome characterization would expedite genetic network analyses and permit the dissection of complex biologic functions. Overall design: The mRNA profiles of primary bone marrow derived macrophages (stimulated by LPS for 3 hours), splenic T cells and B cells from 8-week old wild type (WT) and Beclin 2 KO mice were generated in duplicate using Illumina HiSeq. The mRNA profiles of tumor samples from Beclin 2 KO mice, and lymph nodes from both WT and Beclin 2 KO mice were also generated in duplicate.ENAprimary cell culture, MGC130048, 3.4.22.-, SGCG_HUMAN, determination, 35 kDa dystrophin-associated glycoprotein, Laboratory, atg6, Mus domesticus, SG-gamma, CASP14, mouse, A4, mini-ICE, CASP-14, House Mouse, TYPE, SGCG, LGMD2C, DAGA4, Primaerzelle, House, Mus, chemical analysis, Mini-ICE, 35DAG, Mus musculus domesticus, sarcoglycan, simple tissue, MAM, gamma-SG, SCG3, Mice, Mus musculus., gamma sarcoglycan, Mus musculus, DmAtg6, DMDA1, Caspase-14 subunit p10, Swiss, mice, Tissue, Swiss Mouse, House Mice, Swiss Mice, Caspase-14 subunit p19, gamma (35kDa dystrophin-associated glycoprotein), MICE, ATG6, CG5429, Laboratory Mice, domesticus, Beclin-1, DMDA, l(3)00096, beclin, DmelCG5429, 35kD dystrophin-associated glycoprotein, SCARMD2, gamma-sarcoglycan, Mouse, assay, Beclin1, Laboratory Mouseprimary cell culture, MGC130048, 3.4.22.-, SGCG_HUMAN, determination, 35 kDa dystrophin-associated glycoprotein, Laboratory, atg6, Mus domesticus, SG-gamma, CASP14, mouse, A4, mini-ICE, CASP-14, House Mouse, TYPE, SGCG, LGMD2C, DAGA4, Primaerzelle, House, Mus, chemical analysis, Mini-ICE, 35DAG, Mus musculus domesticus, sarcoglycan, simple tissue, MAM, gamma-SG, SCG3, Mice, Mus musculus., gamma sarcoglycan, Mus musculus, DmAtg6, DMDA1, Caspase-14 subunit p10, Swiss, mice, Tissue, Swiss Mouse, House Mice, Swiss Mice, Caspase-14 subunit p19, gamma (35kDa dystrophin-associated glycoprotein), MICE, ATG6, CG5429, Laboratory Mice, domesticus, Beclin-1, DMDA, l(3)00096, beclin, DmelCG5429, 35kD dystrophin-associated glycoprotein, SCARMD2, gamma-sarcoglycan, Mouse, assay, Beclin1, Laboratory MousefalseRNAseq analysis of tissue and primary cell transcriptomes from wild type and Beclin 2 KO mice.RNAseq analysis of tissue and primary cell transcriptomes from wild type and Beclin 2 KO mice.2025-09-242021-03-07PRJNA437320GSE11153910090