{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["MPI for Metabolism Research"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA450747"],"scientific_name":["Mus musculus"],"long_description":["Obesity increases colorectal cancer despite other disturbances. We have used the AOM/DSS protocol to induce colitis-associated cancer in normal chow diet and high fat diet fed animals. Tumors were microdissected and global gene expression was analysed using microarray. Overall design: Upon weaning animals were either fed a normal chow (NCD) or a high fat diet (HFD) for 14 weeks. Azoxymethane (AOM) (10mg/kg) was injected at week 8 and 4 days later 1.5% dextrane sodium sulphate (DSS) was supplied in the drinking water for 5 days. Mice were sacrificed 62 days after AOM injection and colorectal tumors were microdissected and processed for RNA isolation."],"repository":["ENA"],"description_synonyms":["3.4.22.-, Colorectal Neoplasm, Carcinoma, LCATA deficiency, Food Patterns, Colorectal Cancer, Laboratory, Neoplasms, Mus domesticus, CASP14, mouse, HF - High fat diet, mini-ICE, CASP-14, Tumor, autosomal dominant, House Mouse, Patterns, alpha-lecithin cholesterol acyltransferase deficiency, Colorectal, colorectal cancer, alpha-lecithin:cholesterol acyltransferase deficiency, House, Mus, High fat diet (finding), Mini-ICE, High Fat Diets., Neoplasm, Diets, Mus musculus domesticus, Diet, CRC, Colorectal Cancers, Mice, High-Fat Diet, High Fat Diet, High-Fat, Partial LCAT deficiency, dyslipoproteinemic corneal dystrophy, Colorectal Tumors, Carcinomas, large bowel cancer, average, Mus musculus, Caspase-14 subunit p10, Food Pattern, Swiss, alpha-LCAT deficiency, mice, Dietary, susceptibility to, Colorectal Carcinoma, Swiss Mouse, High Fat, Colorectal Carcinomas, House Mice, Swiss Mice, Caspase-14 subunit p19, Cancers, Colorectal Tumor, MICE, cancer of large bowel, large intestine cancer, Laboratory Mice, domesticus, Food, cancer of the large intestine, Pattern, High-Fat Diets, FED, colon cancer, Dietary Patterns, cancer of the large bowel, fish-eye disease, Mouse, cancer of large intestine, Dietary Pattern, Laboratory Mouse, somatic mutation, colorectal (colon or rectal) cancer, Tumors, Cancer"],"name_synonyms":["3.4.22.-, Colorectal Neoplasm, Carcinoma, LCATA deficiency, Food Patterns, Colorectal Cancer, Laboratory, Neoplasms, Mus domesticus, CASP14, mouse, HF - High fat diet, mini-ICE, CASP-14, Tumor, autosomal dominant, House Mouse, Patterns, alpha-lecithin cholesterol acyltransferase deficiency, Colorectal, colorectal cancer, alpha-lecithin:cholesterol acyltransferase deficiency, House, Mus, High fat diet (finding), Mini-ICE, High Fat Diets., Neoplasm, Diets, Mus musculus domesticus, Diet, CRC, Colorectal Cancers, Mice, High-Fat Diet, High Fat Diet, High-Fat, Partial LCAT deficiency, dyslipoproteinemic corneal dystrophy, Colorectal Tumors, Carcinomas, large bowel cancer, average, Mus musculus, Caspase-14 subunit p10, Food Pattern, Swiss, alpha-LCAT deficiency, mice, Dietary, susceptibility to, Colorectal Carcinoma, Swiss Mouse, High Fat, Colorectal Carcinomas, House Mice, Swiss Mice, Caspase-14 subunit p19, Cancers, Colorectal Tumor, MICE, cancer of large bowel, large intestine cancer, Laboratory Mice, domesticus, Food, cancer of the large intestine, Pattern, High-Fat Diets, FED, colon cancer, Dietary Patterns, cancer of the large bowel, fish-eye disease, Mouse, cancer of large intestine, Dietary Pattern, Laboratory Mouse, somatic mutation, colorectal (colon or rectal) cancer, Tumors, Cancer"],"additional_accession":[]},"is_claimable":false,"name":"Expression data from murine colorectal tumors of mice fed a normal chow diet and a high fat diet","description":"Expression data from murine colorectal tumors of mice fed a normal chow diet and a high fat diet","dates":{"last_updated":"2025-09-24","first_public":"2019-01-19"},"accession":"PRJNA450747","cross_references":{"GEO":["GSE113303"],"taxon":["10090"]}}