{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["IZKF Aachen, RWTH Aachen University"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA471336"],"scientific_name":["Mus musculus"],"long_description":["The Ash2l protein is a member of KMT2 enzyme complexes, which catalyse the (tri-)methylation of lysine 4 of Histone H3. H3K4me3 is considered a marker of actively transcribed genes. We determined changes in gene expression as a consequence of a conditional loss of Ash2l in the bone marrow. The expression data from the bone marrows of mice with floxed Ash2l exon 4 alleles without (control) or with an Mx1-Cre transgene (KO) and treated with synthetic dsRNA to induce recombination and the loss of Ash2l protein expression were compared. Overall design: The expression data from LSK cells of the bone marrow from 3 control and 3 Ash2l KO mice were analysed and the fold changes calculated."],"tag":["xref:PubMed:31164666"],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Consequences of a loss of Ash2l in the bone marrow.","description":"Consequences of a loss of Ash2l in the bone marrow.","dates":{"last_updated":"2025-09-24","first_public":"2019-06-17"},"accession":"PRJNA471336","cross_references":{"GEO":["GSE114433"],"taxon":["10090"],"PubMed":["31164666"]}}