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Neurobiology, Harvard Medical School"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA473501"],"scientific_name":["Mus musculus"],"long_description":["Molecular heterogeneity among spiral ganglion neurons (SGNs) in the mouse cochlea was investigated in two genetic backgrounds: 1) wildtype, 2) Vglut3-/-, which lack inner hair cell-driven glutamatergic activation of SGNs. Overall design: Individual spiral-ganglion neurons expressing the fluorescent reporter tdTomato were dissociated and manually placed into PCR tubes single-cell libraries were made by the Smart-seq2 approach sequencing was done using the NextSeq platform (Illumina) at an average read depth of 4.5 million bioinformatic analysis was conducted in R. Genotypes: bhlhb5::cre/+ Ai14/+ (wildtype) and bhlhb5::cre/+ Ai14/+ Vglut3-/- (Vglut3-/-). Age: P25-P27"],"tag":["xref:PubMed:30078709"],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Single-cell RNA-seq of spiral ganglion neurons from wildtype and Vglut3-/- mice","description":"Single-cell RNA-seq of spiral ganglion neurons from wildtype and Vglut3-/- mice","dates":{"last_updated":"2025-09-24","first_public":"2018-08-08"},"accession":"PRJNA473501","cross_references":{"GEO":["GSE114997"],"taxon":["10090"],"PubMed":["30078709"]}}