ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR742/000/SRR7421580/SRR7421580_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR742/001/SRR7421581/SRR7421581_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR742/007/SRR7421577/SRR7421577_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR742/008/SRR7421578/SRR7421578_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR742/001/SRR7421581/SRR7421581_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR742/007/SRR7421577/SRR7421577_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR742/006/SRR7421576/SRR7421576_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR742/000/SRR7421580/SRR7421580_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR742/006/SRR7421576/SRR7421576_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR742/009/SRR7421579/SRR7421579_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR742/009/SRR7421579/SRR7421579_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR742/008/SRR7421578/SRR7421578_1.fastq.gzprimaryOK200GenomicsCell and Molecular Biology, Tulane Universityhttps://www.ebi.ac.uk/ena/browser/view/PRJNA477826Mus musculusTo identify potential biological targets of the TGFβ pathway involved in AVM formation, we performed RNA-seq on endothelial cells (ECs) isolated from a Smad4 inducible, EC specific knockout (Smad4-iECKO Smad4f/f Cdh5-CreERT2) mouse model that develops retinal AVMs. Overall design: We sequenced a total of 6 samples. We used three wild type samples (Smad4f/f- samples names: Lit38s45, Lit38s6, Lit40s56) and three mutant samples (Smad4f/f Cdh5-CreERT2- sample names: Lit38s12, Lit38s37, Lit40s12). For more detailed information please see supplemental document: GSE116230_Smad4ff_vs_Smad4iECKO.report.pdfxref:PubMed:30744395ENAfalseRNA-Seq: Smad4-iECKO vs Smad4f/f P7 isolated retinal endothelial cells (iECKO=inducible, endothelial cell specific knockout)RNA-Seq: Smad4-iECKO vs Smad4f/f P7 isolated retinal endothelial cells (iECKO=inducible, endothelial cell specific knockout)2025-09-242019-01-03PRJNA477826GSE1162301009030744395