{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["The Second Affiliated Hospital, Harbin Medical University"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA480811"],"scientific_name":["Homo sapiens"],"long_description":["We explored the whole expression profiles of transcriptome included miRNA, circRNA, lncRNA and mRNA in 5 pairs of LSCC and matched non-LSCC tissues by microarray The LSCC-related competing endogenous RNA (ceRNA) networks were constructed based on these microarray data. Overall design: We simultaneously detected the expression profiles of the whole transcriptome, including miRNA, circRNA and lncRNA+mRNA, in five paired laryngeal squamous cell carcinoma (LSCC)and matched non-carcinoma tissues by microarrays. The lncRNA-miRNA-mRNA and circRNA-miRNA-mRNA ceRNA network were constructed using both physical interactions and expression correlations. When cirRNAs in the circRNA-miRNA-mRNA ceRNET and lncRNAs in the lncRNA-miRNA-mRNA ceRNET shared the same miRNA-mRNA interactions, these pairs were retained to construct the circRNA-lncRNA co-regulated ceRNA network. Nine modules were further identified in the network"],"repository":["ENA"],"description_synonyms":["Non Protein Coding, Carcinoma, RNA, Squamous Cell Carcinoma of the Mouth, Transcriptome, Nontranslated RNA, npcRNA, Squamous Cell Carcinoma of the Nasal Cavity, determination, Non Peptide Coding, Transcriptome Profile, stRNA, Expression Profiles, Squamous Cell Carcinoma of the Head and Neck, Small Temporal RNA, Gene Expression Profile, Gene, Head And Neck, Profiles, Primary, Squamous Cell Carcinoma, Squamous Cell Carcinoma of the Larynx, Hypopharyngeal Squamous Cell Carcinoma, whole transcriptome, Noncoding RNA, Gene Expression, Small, Non-Peptide-Coding RNA, Micro RNA, Non-Coding RNA, Expression Signatures, chemical analysis, Gene Expression Signatures, Oral Squamous Cell Carcinoma, Primary., Gene Expression Signature, HNSCC, pre-miRNA, Non-Peptide-Coding, Untranslated RNA, Expression Profile, Transcriptome Profiles, pri miRNA, Oropharyngeal Squamous Cell Carcinoma, miRNAs, Small Temporal, Micro, Non-Coding, Non-Protein-Coding RNA, Temporal RNA, Profile, Laryngeal Squamous Cell Carcinoma, INSDC_qualifier:other, Oral Tongue Squamous Cell Carcinoma, Primary MicroRNA, Head And Neck Squamous Cell Carcinomas, Nontranslated, Oral Squamous Cell Carcinomas, Non-Protein-Coding, miRNA, Primary miRNA, Signatures, INSDC_feature:ncRNA, pri-miRNA, Oral Cavity Squamous Cell Carcinoma, Non Coding, Expression Signature, Gene Expression Profiles, Squamous Cell Carcinoma of Larynx, Transcriptomes, Noncoding, MicroRNA, Head and Neck Squamous Cell Carcinoma, assay, Signature, Squamous Cell of Head and Neck, pre miRNA, LXSC"],"name_synonyms":["Non Protein Coding, Carcinoma, RNA, Squamous Cell Carcinoma of the Mouth, Transcriptome, Nontranslated RNA, npcRNA, Squamous Cell Carcinoma of the Nasal Cavity, determination, Non Peptide Coding, Transcriptome Profile, stRNA, Expression Profiles, Squamous Cell Carcinoma of the Head and Neck, Small Temporal RNA, Gene Expression Profile, Gene, Head And Neck, Profiles, Primary, Squamous Cell Carcinoma, Squamous Cell Carcinoma of the Larynx, Hypopharyngeal Squamous Cell Carcinoma, whole transcriptome, Noncoding RNA, Gene Expression, Small, Non-Peptide-Coding RNA, Micro RNA, Non-Coding RNA, Expression Signatures, chemical analysis, Gene Expression Signatures, Oral Squamous Cell Carcinoma, Primary., Gene Expression Signature, HNSCC, pre-miRNA, Non-Peptide-Coding, Untranslated RNA, Expression Profile, Transcriptome Profiles, pri miRNA, Oropharyngeal Squamous Cell Carcinoma, miRNAs, Small Temporal, Micro, Non-Coding, Non-Protein-Coding RNA, Temporal RNA, Profile, Laryngeal Squamous Cell Carcinoma, INSDC_qualifier:other, Oral Tongue Squamous Cell Carcinoma, Primary MicroRNA, Head And Neck Squamous Cell Carcinomas, Nontranslated, Oral Squamous Cell Carcinomas, Non-Protein-Coding, miRNA, Primary miRNA, Signatures, INSDC_feature:ncRNA, pri-miRNA, Oral Cavity Squamous Cell Carcinoma, Non Coding, Expression Signature, Gene Expression Profiles, Squamous Cell Carcinoma of Larynx, Transcriptomes, Noncoding, MicroRNA, Head and Neck Squamous Cell Carcinoma, assay, Signature, Squamous Cell of Head and Neck, pre miRNA, LXSC"],"additional_accession":[]},"is_claimable":false,"name":"Comprehensive analysis of the whole coding and noncoding RNA transcriptome expression profiles and construction of the circRNA-lncRNA co-regulated ceRNA network in laryngeal squamous cell carcinoma [miRNA]","description":"Comprehensive analysis of the whole coding and noncoding RNA transcriptome expression profiles and construction of the circRNA-lncRNA co-regulated ceRNA network in laryngeal squamous cell carcinoma [miRNA]","dates":{"last_updated":"2025-09-24","first_public":"2020-07-11"},"accession":"PRJNA480811","cross_references":{"GEO":["GSE116994"],"taxon":["9606"]}}