{"database":"ENA","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Fastqsanger.gz":["ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR866/003/SRR8662713/SRR8662713_2.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR866/004/SRR8662714/SRR8662714_1.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR866/003/SRR8662713/SRR8662713_1.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR866/004/SRR8662714/SRR8662714_2.fastq.gz"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["immunology, PUMC"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA525363"],"scientific_name":["Mus musculus"],"long_description":["To identify new target genes of miR-1, the affinity based purification experiments of mouse mRNAs using biotin-labeled miR-1 as probes was performed in peritoneal macorphages. Enriched RNAs and input samples were then subjected to RNA sequencing using an Illumina platform. Overall design: To de novo explore miR-1 target genes in peritnoeal macrophage cells, we performed a modified miRIP protocol using biotin-labeled miR-1 as oligo nucleotide probes to in vivo affinity purify the genes using nucleic acid hybridization and use Illumina Next Generation Sequencing assay to identify the associated RNAs."],"repository":["ENA"],"description_synonyms":["biochemical pathways, macrophagocyte, single-organism catabolic process, multicellular organismal catabolic process, cellular breakdown, RNA, degradation, Monocyte Derived Macrophages, Polyadenylated, STAT91, typical plasmatocyte, Messenger RNA, IFNA@, Monocyte Derived, XStat1, monocyte-derived macrophage, cellular catabolism, DD6G4-4, IFNA13, Monocyte-Derived, Non-Polyadenylated mRNA., macrophage, ISGF-3, Messenger, Poly(A)+ mRNA, responsivity, Monocyte-Derived Macrophage, INSDC_feature:mRNA, cellular degradation, Signal transducer and activator of transcription 1-alpha/beta, secretion, Polyadenylated RNA, agranular plasmatocyte, Non Polyadenylated, breakdown of molecule, Monocyte-Derived Macrophages, Macrophage, Polyadenylated Messenger RNA, reactivity, Poly(A)+ RNA, Non Polyadenylated mRNA, breakdown, CANDF7, protein_coding_transcript, biodegradation, IFN-alphaD, mRNA, Poly(A) Tail, breakdown of chemical, catabolism, Macrophages, 2010005J02Rik, IFL, Polyadenylated Messenger, IFN, Non-Polyadenylated, messenger RNA, Bone Marrow Derived Macrophages, Bone Marrow-Derived Macrophage, Bone Marrow-Derived, breakdown of substance, template RNA, STAT1, lamellocyte, IMD31B, IMD31C, IMD31A, Bone Marrow-Derived Macrophages, AA408197, granulocyte, biotransformation, histiocyte, response, Polyadenylated mRNA, transcription factor ISGF-3 components p91/p84, Poly(A) RNA, IFN-ALPHA"],"name_synonyms":["biochemical pathways, macrophagocyte, single-organism catabolic process, multicellular organismal catabolic process, cellular breakdown, RNA, degradation, Monocyte Derived Macrophages, Polyadenylated, STAT91, typical plasmatocyte, Messenger RNA, IFNA@, Monocyte Derived, XStat1, monocyte-derived macrophage, cellular catabolism, DD6G4-4, IFNA13, Monocyte-Derived, Non-Polyadenylated mRNA., macrophage, ISGF-3, Messenger, Poly(A)+ mRNA, responsivity, Monocyte-Derived Macrophage, INSDC_feature:mRNA, cellular degradation, Signal transducer and activator of transcription 1-alpha/beta, secretion, Polyadenylated RNA, agranular plasmatocyte, Non Polyadenylated, breakdown of molecule, Monocyte-Derived Macrophages, Macrophage, Polyadenylated Messenger RNA, reactivity, Poly(A)+ RNA, Non Polyadenylated mRNA, breakdown, CANDF7, protein_coding_transcript, biodegradation, IFN-alphaD, mRNA, Poly(A) Tail, breakdown of chemical, catabolism, Macrophages, 2010005J02Rik, IFL, Polyadenylated Messenger, IFN, Non-Polyadenylated, messenger RNA, Bone Marrow Derived Macrophages, Bone Marrow-Derived Macrophage, Bone Marrow-Derived, breakdown of substance, template RNA, STAT1, lamellocyte, IMD31B, IMD31C, IMD31A, Bone Marrow-Derived Macrophages, AA408197, granulocyte, biotransformation, histiocyte, response, Polyadenylated mRNA, transcription factor ISGF-3 components p91/p84, Poly(A) RNA, IFN-ALPHA"],"additional_accession":[]},"is_claimable":false,"name":"Inducible degradation of Sros1 promotes IFN-γ-activated macrophage innate response by stabilizing STAT1 mRNA","description":"Inducible degradation of Sros1 promotes IFN-γ-activated macrophage innate response by stabilizing STAT1 mRNA","dates":{"last_updated":"2025-09-24","first_public":"2019-09-20"},"accession":"PRJNA525363","cross_references":{"GEO":["GSE127769"],"taxon":["10090"]}}