{"database":"ENA","file_versions":[],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Medical University Vienna"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA525984"],"scientific_name":["Homo sapiens"],"tag":["xref:PubMed:31570701"],"long_description":["The secretome of y-irradiated peripheral blood mononuclear cells (PBMC) is well known for its pleiotropic effects on tissue protection and regeneration. Irradiation of PBMC lead to necroptosis of a certain amount of PBMC in a cell-sorter analysis. The aim of this study was to investiage the trancriptomic changes of PBMC and PBMC subsets (CD4, CD8, CD19, CD56, CD14) in response to y-irradiation Overall design: In total 72 samples obtained from four healthy donors were analysed (0h= cells immediately after purification, 24h_0Gy = cells cultivated for 24 hours without prior radiation 24h_60Gy = cell cultivated for 24 hours after irradiation with 60Gy). At each time point six different cell populations were analysed (unseparated PBMC, and separated PBMC subsets: CD4, CD8, CD14 CD19 CD56)."],"repository":["ENA"],"description_synonyms":["Peripheral Blood Human Mononuclear Cells, Peripheral Blood Mononuclear Cell, Mononuclear Leukocyte., Leukocyte, Mononuclear, function, Mononuclear Leukocytes, PBMC Peripheral Blood Mononuclear Cells, Peripheral Blood Mononuclear Cells"],"name_synonyms":["Peripheral Blood Human Mononuclear Cells, Peripheral Blood Mononuclear Cell, Mononuclear Leukocyte., Leukocyte, Mononuclear, function, Mononuclear Leukocytes, PBMC Peripheral Blood Mononuclear Cells, Peripheral Blood Mononuclear Cells"],"additional_accession":[]},"is_claimable":false,"name":"Changes in the biologica function of necroptotic, peripheral blood mononuclear cells under irradiation in vitro","description":"Changes in the biologica function of necroptotic, peripheral blood mononuclear cells under irradiation in vitro","dates":{"last_updated":"2025-09-24","first_public":"2019-10-10"},"accession":"PRJNA525984","cross_references":{"GEO":["GSE127982"],"taxon":["9606"],"PubMed":["31570701"]}}