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Overall design: RNA sequencing was performed on control and RNF113A-depleted A549 cells treated or not with Cisplatin. Three biological replicates were prepared for each condition."],"repository":["ENA"],"description_synonyms":["brittle hair, DNA Injury, Genotoxic Stress, DNA Injuries, trichothiodystrophy syndrome, Injury, Materials, Genetic, 2810428C21Rik, decreased fertility, Rnf113a, RNF113, DNA Lesion, Gene, and short stature, INSDC_feature:gene, Viabilities, Cistrons, Cell, Tay syndrome, Cell Viabilities, IBIDS syndrome, DNA Lesions, trichothiodystrophy with congenital ichthyosis, AI426758, ZNF183, Genotoxic, trichothiodystrophy, trichothiodystrophy with congenital ichtyosis, Material, spliceosome, intellectual impairment, Survival, Ichtyosis, Stress, Spliceosome, Genetic Materials, Cistron, Cwc24, DNA., sulfur-deficient brittle hair syndrome, 2310020H19Rik, spliceosome complex, Cell Viability, Genetic Material, Viability"],"name_synonyms":["brittle hair, DNA Injury, Genotoxic Stress, DNA Injuries, trichothiodystrophy syndrome, Injury, Materials, Genetic, 2810428C21Rik, decreased fertility, Rnf113a, RNF113, DNA Lesion, Gene, and short stature, INSDC_feature:gene, Viabilities, Cistrons, Cell, Tay syndrome, Cell Viabilities, IBIDS syndrome, DNA Lesions, trichothiodystrophy with congenital ichthyosis, AI426758, ZNF183, Genotoxic, trichothiodystrophy, trichothiodystrophy with congenital ichtyosis, Material, spliceosome, intellectual impairment, Survival, Ichtyosis, Stress, Spliceosome, Genetic Materials, Cistron, Cwc24, DNA., sulfur-deficient brittle hair syndrome, 2310020H19Rik, spliceosome complex, Cell Viability, Genetic Material, Viability"],"additional_accession":[]},"is_claimable":false,"name":"The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage","description":"The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage","dates":{"last_updated":"2025-09-24","first_public":"2020-03-24"},"accession":"PRJNA549715","cross_references":{"GEO":["GSE133029"],"taxon":["9606"],"PubMed":["32152280"]}}