ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR967/009/SRR9674449/SRR9674449.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR967/008/SRR9674448/SRR9674448.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR967/000/SRR9674440/SRR9674440.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR967/006/SRR9674446/SRR9674446.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR967/001/SRR9674441/SRR9674441.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR967/005/SRR9674445/SRR9674445.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR967/004/SRR9674444/SRR9674444.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR967/002/SRR9674442/SRR9674442.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR967/009/SRR9674439/SRR9674439.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR967/007/SRR9674447/SRR9674447.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR967/000/SRR9674450/SRR9674450.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR967/003/SRR9674443/SRR9674443.fastq.gzprimaryOK200GenomicsLe Romancer, Cancer Cell Plasticity, Cancer Research Center of Lyonhttps://www.ebi.ac.uk/ena/browser/view/PRJNA554259Homo sapiensUsing a genome-wide analysis, we demonstrated that PRMT1 is selectively required for progesterone-regulated expression of PR target genes, implicated in cell proliferation and migration. Overall design: We examined whether PRMT1 is required for progesterone-induced expression of genes, by depleting PRMT1 in T47D breast cancer cells, using siRNA. We examined gene expression changes at 6 hours progesterone (R5020) treatment compared with ethanol treatment as a control. siRNA for a nonspecific sequence (siCT) followed by 6h of R5020 treatment was performed as control.ENAfalsePRMT1 differentially regulates gene expression in T47D-breast cancer cellsPRMT1 differentially regulates gene expression in T47D-breast cancer cells2025-09-242020-06-14PRJNA554259GSE1341949606