ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR100/056/SRR10002656/SRR10002656.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR100/059/SRR10002659/SRR10002659.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR100/057/SRR10002657/SRR10002657.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR100/058/SRR10002658/SRR10002658.fastq.gzprimaryOK200GenomicsUniversity of Washingtonhttps://www.ebi.ac.uk/ena/browser/view/PRJNA561035Localization of the AAVS1 locus in AAVS transgenic mice:Inverse PCR (iPCR) for integration site analysis requires the knowledge of the AAVS1 locus localization in the genome of AAVS1/CD46-transgenic mice. To determine this, we used a targeted locus amplification (TLA)/PCR technology that involves thecrosslinking of physically proximal sequences. The TLA data obtainedfrom bone marrow cells from AAVS1/CD46-tg mice were then aligned with a reference mouse genome (mm10).TLA results indicate that the AAVS1 transgene is integrated into chromosome 14 at the location(Chr14:110443871-110461834), accompanied by a 18Kb deletion of mouse genome sequence.ENAMus musculus, 3.4.22.-, Caspase-14 subunit p10, Laboratory, Swiss, mice, Mus domesticus, Swiss Mouse, CASP14, mouse, mini-ICE, House Mice, Swiss Mice, Caspase-14 subunit p19, CASP-14, MICE, House Mouse, Laboratory Mice, domesticus, House, Mus, Mini-ICE, Mus musculus domesticus, site, TG, Mouse, Mice, Laboratory Mouse, region, Mus musculus.falseAAVS locus site identification in AAVS1-transgenic mice2023-05-192019-08-21PRJNA561035