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Regulation lab, UMR9002 CNRS-UMhttps://www.ebi.ac.uk/ena/browser/view/PRJNA600988Homo sapienswe used the technnology of ChIP-sequencing to sepcifically analyze the recruitment of the MRN Complex onto target genes in conjunction with RNAPII, investigating the effect of the depletion of MRN complex on RNAPII and active transcription Overall design: HeLa were treated with shRNA or with DRB, or were heatshocked, and the different factors were ChIPedxref:PubMed:34020942ENAMRE11, l(3)e77A1, ATNBS1, Circulatory, Mre11, broad, NBS, Nbs, Failure, Circulatory Collapse, ATMRE11, CG16928, Hot, 16928, Heat, CG1691, 6754, DmelCG16928, nbs, Shock, treatment, SP143, l(3)67BDr, Genomes, Jon99B, l(3)67BDp, Jon99C, DmelCG31362, HeLa, Jon99Calpha, ARABIDOPSIS MEIOTIC RECOMBINATION 11, 99Calpha, Hypovolemic Shock, mre11-a, CG31362, Hypovolemic, DmelCG6754, P95, disease management, Therapies, HJ2, Jon99Calphaii, IMP-1, DmelCG1691, Therapy, Jon99Cbetaiii, ATV, Jon99C2, wide/broad, Jon99C1, nijmegen breakage syndrome 1, ORE-9, XRS4, Maps, NGS1, Circulatory Failure, JonC, Cell, MDK4_8, slr10, anon-EST:fe2B3, Ser99Db, CG15519, F16B3_31, Temperatures, HeLa Cell, MDK4.8, IMP, F16B3.31, mre11, IGF-II, MEIOTIC RECOMBINATION 11, Temperature, Jon99Cbeta, AT-V2, imp, AT-V1, CG6754, Ser5, cg1691, SER2, Ser2, NBS1, Nbs1, whole genome, Mre11b, HeLa., l(1)G0072, Treatments, Collapse, nbs1, wide, HNGS1, dIMP, Dnbs1, MRE11A, Therapeutic, MRE11B, Cells, Hot Temperatures, Treatment, anon-WO0140519.39, ATLD, RAD58MRE11, l(3)e77A1, ATNBS1, Circulatory, RNA pol II, 8WG16, Mre11, broad, NBS, Nbs, Failure, II, Circulatory Collapse, ATMRE11, Pol II, CG16928, RNA polII, l(1)L5, RNApol2, POL, Hot, RNA pol IIo, 16928, Heat, CG1691, Pol IIo[Ser2], 5, 6754, DmelCG16928, nbs, Shock, treatment, SP143, RNApolII, l(3)67BDr, Genomes, Jon99B, RNAP, Pol II CTD, l(3)67BDp, Jon99C, DmelCG31362, HeLa, RPII215, RNAPII0, Jon99Calpha, ARABIDOPSIS MEIOTIC RECOMBINATION 11, Ubl, 99Calpha, Hypovolemic Shock, mre11-a, CG31362, Hypovolemic, RNAP II, DmelCG6754, L5, P95, disease management, l(1)DF912, Therapies, HJ2, RNA Pol II CTD, polII, CG1554, Pol IIo[ser5], Jon99Calphaii, IMP-1, Pol II0[ser2], l(1)G0040, DmelCG1691, RNA PolII, Therapy, Pol IIo, Jon99Cbetaiii, ATV, Jon99C2, wide/broad, Jon99C1, nijmegen breakage syndrome 1, Pol IIa, ORE-9, XRS4, Maps, NGS1, l(1)DC912, PolII, Circulatory Failure, JonC, RNAPII, Cell, MDK4_8, slr10, anon-EST:fe2B3, Ser99Db, CG15519, F16B3_31, Temperatures, HeLa Cell, MDK4.8, IMP, F16B3.31, mre11, Rpll215, IGF-II, pol II, MEIOTIC RECOMBINATION 11, Pol-IIa, Temperature, DmelCG1554, Jon99Cbeta, Rpb1, RNA Pol II, RPB1, AT-V2, imp, AT-V1, Pol IIo[ser2], PolIIo, CG6754, RNAP II LS, Ser5, cg1691, SER2, Ser2, NBS1, Nbs1, whole genome, Mre11b, RpII, HeLa., l(1)G0072, Treatments, Pol II0[ser5], l(1)10Ca, Collapse, nbs1, Pol II Ser5P, Pol II[ser2], wide, HNGS1, dIMP, Dnbs1, MRE11A, Therapeutic, MRE11B, H5, Cells, CTD, Hot Temperatures, Treatment, anon-WO0140519.39, ATLD, dRPB1, RNA PolI 215, dRpb1, RAD58falseGenome-wide maps of MRE11, NBS1 total RNAPII and phospho-Ser2-RNAPII in WT cells, upon shControl, shMRE11 or shNBS1 treatment, after treatment by DRB and after heat shock in HeLa cellsGenome-wide maps of MRE11, NBS1 total RNAPII and phospho-Ser2-RNAPII in WT cells, upon shControl, shMRE11 or shNBS1 treatment, after treatment by DRB and after heat shock in HeLa cells2025-09-242021-01-14PRJNA600988GSE143591960634020942