{"database":"ENA","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Fastqsanger.gz":["ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR112/027/SRR11237927/SRR11237927.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR112/026/SRR11237926/SRR11237926.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR112/028/SRR11237928/SRR11237928.fastq.gz"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["School of life science, Tsinghua University"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA610302"],"scientific_name":["Danio rerio"],"long_description":["To study the function of zebrafish nuclear pores during early embryogenesis, we generated maternal zygotic double mutant of nup85 nup133 (MZnup85 nup133) using CRISPR/Cas9 and report the transcriptome-wide changes in comparison to wild-type (WT) embryos. Our analysis reveals a dramatic delay of maternal mRNA degradation and zygotic genome activation in MZnup85 nup133 embryos during maternal-to-zygotic transition. Overall design: mRNA profile of zebrafish WT and MZnup85 nup133 embryos at 4.3 hpf or at stage with dome morphology"],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptome analysis of wild-type and maternal zygotic double mutant of nup85 nup133 zebrafish embryos during early development","description":"Transcriptome analysis of wild-type and maternal zygotic double mutant of nup85 nup133 zebrafish embryos during early development","dates":{"last_updated":"2025-09-24","first_public":"2023-03-06"},"accession":"PRJNA610302","cross_references":{"GEO":["GSE146394"],"taxon":["7955"]}}