{"database":"ENA","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Fastqsanger.gz":["ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR117/053/SRR11743953/SRR11743953.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR117/052/SRR11743952/SRR11743952.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR117/050/SRR11743950/SRR11743950.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR117/051/SRR11743951/SRR11743951.fastq.gz"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["Buchmann Institute for Molecular Life Sciences (BMLS), Goethe University Frankfurt"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA631368"],"scientific_name":["Homo sapiens"],"tag":["xref:PubMed:33376132"],"long_description":["The downregulation of diabetes susceptibility gene GLIS3 contributes to pancreatic beta cell demise, at least in part, through downregulation of the splicing factor SRSF6. Here, we used individual-nucleotide UV crosslinking and immunoprecipitation (iCLIP) to map the RNA binding landscape of SRSF6 in pancreatic beta cells. Overall design: Four independent iCLIP replicates for endogeneous SRSF6 from human pancreatic beta cells (EndoC-βH1 cell line)"],"repository":["ENA"],"name_synonyms":["Modb1, Regulations, Sfrs6, nuclear mRNA cis splicing, Materials, MUTYH-Associated Polyposis, SRP55, DM, methionine aminopeptidase activity, Social Controls., Formal Social Control, MYH-associated polyposis, autosomal recessive familial adenomatous polyposis, Maps, Gene, Ximpact, Cistrons, impact-a, diabetes mellitus (disease), OB-RGRP, Social Control, Diabetes mellitus (disorder), 2, IMPACT, imprinted and ancient gene protein homolog, Genetic Materials, NOS, Leprb, Formal Social Controls, familial adenomatous polyposis, Genetic Material, MAP, peptidase M activity, autosomal recessive, DM - Diabetes mellitus, adenomas, imprinted and ancient gene protein, LEPROT, HEL-S-91, RUTBC3, rabGAPLP, susceptibility, L-methionine aminopeptidase activity, Genetic, diabetes mellitus, familial adenomatous polyposis 2, AI314910, SFRS6, Control, RabGAP-5, obese-like, 1210001E11Rik, MYH-Associated Polyposis, Controls, Obr, B52, RABGAP5, Diabetes NOS, autosomal recessive multiple colorectal adenomas, Social, via U2-type spliceosome, AW146126, Diabetes mellitus, Material, RUSC3, multiple colorectal, MAP syndrome, Cistron, regulation, obl, E430016J11Rik, Regulation, Diabetes, RWDD5, FAP2, diabetes, db, colorectal adenomatous polyposis"],"description_synonyms":["Modb1, Regulations, Sfrs6, nuclear mRNA cis splicing, Materials, MUTYH-Associated Polyposis, SRP55, DM, methionine aminopeptidase activity, Social Controls., Formal Social Control, MYH-associated polyposis, autosomal recessive familial adenomatous polyposis, Maps, Gene, Ximpact, Cistrons, impact-a, diabetes mellitus (disease), OB-RGRP, Social Control, Diabetes mellitus (disorder), 2, IMPACT, imprinted and ancient gene protein homolog, Genetic Materials, NOS, Leprb, Formal Social Controls, familial adenomatous polyposis, Genetic Material, MAP, peptidase M activity, autosomal recessive, DM - Diabetes mellitus, adenomas, imprinted and ancient gene protein, LEPROT, HEL-S-91, RUTBC3, rabGAPLP, susceptibility, L-methionine aminopeptidase activity, Genetic, diabetes mellitus, familial adenomatous polyposis 2, AI314910, SFRS6, Control, RabGAP-5, obese-like, 1210001E11Rik, MYH-Associated Polyposis, Controls, Obr, B52, RABGAP5, Diabetes NOS, autosomal recessive multiple colorectal adenomas, Social, via U2-type spliceosome, AW146126, Diabetes mellitus, Material, RUSC3, multiple colorectal, MAP syndrome, Cistron, regulation, obl, E430016J11Rik, Regulation, Diabetes, RWDD5, FAP2, diabetes, db, colorectal adenomatous polyposis"],"additional_accession":[]},"is_claimable":false,"name":"Identification of SRSF6 splicing regulatory map and its impact on diabetes susceptibility genes regulation","description":"Identification of SRSF6 splicing regulatory map and its impact on diabetes susceptibility genes regulation","dates":{"last_updated":"2025-09-24","first_public":"2020-12-24"},"accession":"PRJNA631368","cross_references":{"GEO":["GSE150172"],"taxon":["9606"],"PubMed":["33376132"]}}