ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR122/097/SRR12203097/SRR12203097.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR122/092/SRR12203092/SRR12203092.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR122/096/SRR12203096/SRR12203096.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR122/095/SRR12203095/SRR12203095.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR122/093/SRR12203093/SRR12203093.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR122/094/SRR12203094/SRR12203094.fastq.gzprimaryOK200GenomicsCarla Kim, Genetics, Harvard Universityhttps://www.ebi.ac.uk/ena/browser/view/PRJNA645692Mus musculusxref:PubMed:32690724The goals of this experiment is to identify transcriptomic changes upon loss of Brg1 in lung adenocarcinoma cells. Overall design: Kras/p53 lung adenocarcinoma tumor derived cell lines were subjected to CRISRP/Cas9-mediated genome editing using guides against sgTomato (control) or sgBrg1 (sample). Isogenic Kras/p53 mutant lung cancer cell lines with and without Brg1 were derived and used for bulk RNA-sequencing. Experiment was performed in triplicate conditions.ENAKI-RAS, beta[[3]]-Tub, Ribonucleic, DmelCG17117, dp53, BRG1, Brg1, determination, p50, Kras2, NS3, p53, snf2, 143391_i_at, beta3 TU, b2b692Clo, SW1|SNF, LFS1, betaTub3, Tp53, l(3)05745, ras, DMP53, bbl, Gene Products, Kras-2, Cell., Dmp53, anon-EST:Liang-2.13, C-K-RAS, Non Polyadenylated, k-ras, RNA Gene Products, KRAS2, SNF2beta, KRAS1, rask2, p21B, 1323/07, clone 2.13, BCC7, SWI2, D.m.BETA-60D, K-RAS4B, K-RAS4A, beta-Tub6D, dmp53, T, DmP53, 1422/04, Dietary Fiber, Non-Polyadenylated RNA, SNF2, baf190, B3t, DmelCG3401, Trp53, Dp53, SW1/SNF, betaTub60C, rtps2, beta3-tubulin, beta[[3]]-tubulin, TRP53, CG17117, swi2, p50/tubulin, beta-Tub60D, CG10873, RNA, Dmbeta3, Dm-HTH, ribose nucleic acid, Ki-ras, K-RAS2B, K-RAS2A, BETA 60D, prac, ribonucleic acids, beta3t, beta3-Tub, snf2b, K-ras, BAF190, RNS, BAF190A, c-Ki-ras, X-brg1, Cell, Xp53, 3t, SPAC29A4.21, RTPS2, snf2lb, yeast nucleic acid, Ribonukleinsaeure, p53/tubulin, snf2l, chemical analysis, p21, HP1-BP72, pentosenucleic acids, Ribonucleic acids, bfy, AI929937, beta[[3]] tubulin, Tub60D, HTH, Hth, hSNF2b, ribonucleic acid, Acid, CG33336, beta-tub, NS, MRD16, Non Polyadenylated RNA, DmelCG33336, D-p53, Non-Polyadenylated, beta60C, CG3401, beta3Tub, beta3TUB, brg1, Dm-P53, l(3)86Ca, snf2l4, Ribonucleic Acid, beta3, b2b508.1Clo, dtl, Tub, DTB3, SNF2L4, Meis1, snf2-beta, hth1, hth2, RASK2, kras, betatub60D, CFC2, P53, SNF2LB, p44, bhy, assay, CG31325, betaTubKI-RAS, beta[[3]]-Tub, Ribonucleic, DmelCG17117, dp53, BRG1, Brg1, determination, p50, Kras2, NS3, p53, snf2, 143391_i_at, beta3 TU, b2b692Clo, SW1|SNF, LFS1, betaTub3, Tp53, l(3)05745, ras, DMP53, bbl, Gene Products, Kras-2, Cell., Dmp53, anon-EST:Liang-2.13, C-K-RAS, Non Polyadenylated, k-ras, RNA Gene Products, KRAS2, SNF2beta, KRAS1, rask2, p21B, 1323/07, clone 2.13, BCC7, SWI2, D.m.BETA-60D, K-RAS4B, K-RAS4A, beta-Tub6D, dmp53, T, DmP53, 1422/04, Dietary Fiber, Non-Polyadenylated RNA, SNF2, baf190, B3t, DmelCG3401, Trp53, Dp53, SW1/SNF, betaTub60C, rtps2, beta3-tubulin, beta[[3]]-tubulin, TRP53, CG17117, swi2, p50/tubulin, beta-Tub60D, CG10873, RNA, Dmbeta3, Dm-HTH, ribose nucleic acid, Ki-ras, K-RAS2B, K-RAS2A, BETA 60D, prac, ribonucleic acids, beta3t, beta3-Tub, snf2b, K-ras, BAF190, RNS, BAF190A, c-Ki-ras, X-brg1, Cell, Xp53, 3t, SPAC29A4.21, RTPS2, snf2lb, yeast nucleic acid, Ribonukleinsaeure, p53/tubulin, snf2l, chemical analysis, p21, HP1-BP72, pentosenucleic acids, Ribonucleic acids, bfy, AI929937, beta[[3]] tubulin, Tub60D, HTH, Hth, hSNF2b, ribonucleic acid, Acid, CG33336, beta-tub, NS, MRD16, Non Polyadenylated RNA, DmelCG33336, D-p53, Non-Polyadenylated, beta60C, CG3401, beta3Tub, beta3TUB, brg1, Dm-P53, l(3)86Ca, snf2l4, Ribonucleic Acid, beta3, b2b508.1Clo, dtl, Tub, DTB3, SNF2L4, Meis1, snf2-beta, hth1, hth2, RASK2, kras, betatub60D, CFC2, P53, SNF2LB, p44, bhy, assay, CG31325, betaTubfalseBulk RNA-sequencing analysis of isogenic murine Kras/p53 (KP) Brg1 wildtype cells versus Brg1 knockout (KPB) cellsBulk RNA-sequencing analysis of isogenic murine Kras/p53 (KP) Brg1 wildtype cells versus Brg1 knockout (KPB) cells2025-09-242020-09-02PRJNA645692GSE1542661009032690724