{"database":"ENA","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Fastqsanger.gz":["ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR124/000/SRR12465900/SRR12465900.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR124/004/SRR12465904/SRR12465904.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR124/005/SRR12465905/SRR12465905.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR124/003/SRR12465903/SRR12465903.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR124/099/SRR12465899/SRR12465899.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR124/097/SRR12465897/SRR12465897.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR124/098/SRR12465898/SRR12465898.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR124/002/SRR12465902/SRR12465902.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR124/096/SRR12465896/SRR12465896.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR124/001/SRR12465901/SRR12465901.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR124/095/SRR12465895/SRR12465895.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR124/094/SRR12465894/SRR12465894.fastq.gz"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["University of Colorado Anschutz Medical Campus"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA657752"],"scientific_name":["Homo sapiens"],"long_description":["The goal of this study was to understand the role of the chromatin factors KDM5A and PHF2 in Ewing Sarcoma progression. Overall design: RNA-seq was used to define the effects of KDM5A and PHF2 depletion on gene expression in the patient-derived Ewing Sarcoma cell line A673."],"tag":["xref:PubMed:33196691"],"repository":["ENA"],"description_synonyms":["Ewing's family localized tumor, peripheral primitive neuroectodermal tumour, TDRD19C, l(3)rK137, Ewing tumour., Sic1, localized Ewing's sarcoma/peripheral primitive neuroectodermal tumor, Materials, RBBP-2, Ewing's sarcoma, postnatal development, localised Ewing sarcoma, AA409370, Gene, growth and development, Tumor, JARID1A, 0763/13, CG17228, MTF2L2, prevention, C76986, l(3)10419, 1135/09, 1135/07, dmTAF8, DmelCG17228, Fli-1, Ewing's tumour, HL-VIII, 0451/09, anon-WO0140519.15, F15E12.6, RBP2, EWSR2, Prosp, prevention and control, Ewings Tumor, FLI, PROS, Ewing's sarcoma/peripheral primitive neuroectodermal tumour, F15E12_6, 0244/09, 0585/13, Genetic, reference sample, FLIL, MUB3_18, DROPROSA, CG7128, MUB3.18, l(3)j6E2, localized Ewing's tumor, CENP-35, GRC5, Ewing's Tumor, Ewing's Family of Tumours, l(3)rH013, preventive measures, 671/2, prod, 0320/10, Sarcoma, Prodos, DMPROSPER, Fli1, localised Ewing's sarcoma/peripheral primitive neuroectodermal tumour, peripheral primitive neuroectodermal tumor, Ewing's tumor, Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, AW557215, TAF, 0563/18, Controlled, 0671/02, PHF2, Phf2, l(3)j12C8, Ewing's Family of Tumors, sarcoma, Controlling, preventive therapy, Ewsh, l(3)rO534, PRO, Pro, localised Ewing's tumour, localised Ewing's sarcoma, Ewing Family of Tumors, Cistrons, CYS, AU018891, l(3)rJ806, Pros, peripheral, localized peripheral primitive neuroectodermal tumor, SIC-1, development, Ewing's sarcoma/peripheral primitive neuroectodermal tumor, l(3)rL433, PNET of Thoracopulmonary Region, PROS-1, Ewings Sarcoma, PROS-2, Ewing's Sarcoma, l(3)rI160, 0441/16, Jarid1a, pro, 1316/02, ES, Tumors of the Ewing's Family, TFIID, BcDNA:HL08040, Genetic Materials, and GLY protein 2, Ewings sarcoma-primitive neuroectodermal tumour, Genetic Material, PCL1, D17Ertd455e, Pcl1, MET, ATCMPG1, ATCMPG2, Ewing sarcoma, and GLY protein 1, bK984G1.4, localised peripheral primitive neuroectodermal tumour, Voila, growth pattern, Ewings sarcoma-primitive neuroectodermal tumor, prophylaxis, non-developmental growth, neuroepithelioma, Ewings sarcoma, 0664/07, 1167/13, postnatal growth, Ewing Tumor, hPHF1, Ewing, Ewing's Sarcoma/Peripheral Primitive Neuroectodermal Tumor, RBBP2, TAF[[II]], Ewings, l(3)rK204, Ews, EWS, metastatic, Rbbp2, Ewing's, JHDM1E, DmelCG7128, control, Material, localized Ewing's sarcoma, Ewing tumor, Ewing's sarcoma (morphologic abnormality), localized Ewing sarcoma, Cistron, l(1)16Fg, TAF8, 0989/01, growth, Tctex3, Ewing Sarcoma, pds"],"name_synonyms":["Ewing's family localized tumor, peripheral primitive neuroectodermal tumour, TDRD19C, l(3)rK137, Ewing tumour., Sic1, localized Ewing's sarcoma/peripheral primitive neuroectodermal tumor, Materials, RBBP-2, Ewing's sarcoma, postnatal development, localised Ewing sarcoma, AA409370, Gene, growth and development, Tumor, JARID1A, 0763/13, CG17228, MTF2L2, prevention, C76986, l(3)10419, 1135/09, 1135/07, dmTAF8, DmelCG17228, Fli-1, Ewing's tumour, HL-VIII, 0451/09, anon-WO0140519.15, F15E12.6, RBP2, EWSR2, Prosp, prevention and control, Ewings Tumor, FLI, PROS, Ewing's sarcoma/peripheral primitive neuroectodermal tumour, F15E12_6, 0244/09, 0585/13, Genetic, reference sample, FLIL, MUB3_18, DROPROSA, CG7128, MUB3.18, l(3)j6E2, localized Ewing's tumor, CENP-35, GRC5, Ewing's Tumor, Ewing's Family of Tumours, l(3)rH013, preventive measures, 671/2, prod, 0320/10, Sarcoma, Prodos, DMPROSPER, Fli1, localised Ewing's sarcoma/peripheral primitive neuroectodermal tumour, peripheral primitive neuroectodermal tumor, Ewing's tumor, Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor, AW557215, TAF, 0563/18, Controlled, 0671/02, PHF2, Phf2, l(3)j12C8, Ewing's Family of Tumors, sarcoma, Controlling, preventive therapy, Ewsh, l(3)rO534, PRO, Pro, localised Ewing's tumour, localised Ewing's sarcoma, Ewing Family of Tumors, Cistrons, CYS, AU018891, l(3)rJ806, Pros, peripheral, localized peripheral primitive neuroectodermal tumor, SIC-1, development, Ewing's sarcoma/peripheral primitive neuroectodermal tumor, l(3)rL433, PNET of Thoracopulmonary Region, PROS-1, Ewings Sarcoma, PROS-2, Ewing's Sarcoma, l(3)rI160, 0441/16, Jarid1a, pro, 1316/02, ES, Tumors of the Ewing's Family, TFIID, BcDNA:HL08040, Genetic Materials, and GLY protein 2, Ewings sarcoma-primitive neuroectodermal tumour, Genetic Material, PCL1, D17Ertd455e, Pcl1, MET, ATCMPG1, ATCMPG2, Ewing sarcoma, and GLY protein 1, bK984G1.4, localised peripheral primitive neuroectodermal tumour, Voila, growth pattern, Ewings sarcoma-primitive neuroectodermal tumor, prophylaxis, non-developmental growth, neuroepithelioma, Ewings sarcoma, 0664/07, 1167/13, postnatal growth, Ewing Tumor, hPHF1, Ewing, Ewing's Sarcoma/Peripheral Primitive Neuroectodermal Tumor, RBBP2, TAF[[II]], Ewings, l(3)rK204, Ews, EWS, metastatic, Rbbp2, Ewing's, JHDM1E, DmelCG7128, control, Material, localized Ewing's sarcoma, Ewing tumor, Ewing's sarcoma (morphologic abnormality), localized Ewing sarcoma, Cistron, l(1)16Fg, TAF8, 0989/01, growth, Tctex3, Ewing Sarcoma, pds"],"additional_accession":[]},"is_claimable":false,"name":"KDM5A and PHF2 positively control expression of pro-metastatic genes repressed by EWS/Fli1, and promote growth and metastatic properties in Ewing Sarcoma","description":"KDM5A and PHF2 positively control expression of pro-metastatic genes repressed by EWS/Fli1, and promote growth and metastatic properties in Ewing Sarcoma","dates":{"last_updated":"2025-09-24","first_public":"2020-09-04"},"accession":"PRJNA657752","cross_references":{"GEO":["GSE156387"],"taxon":["9606"],"PubMed":["33196691"]}}