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Systems Institute, University of Exeter"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA720968"],"scientific_name":["Homo sapiens"],"long_description":["Human naïve pluripotent cells can differentiate to extraembryonic trophoblast and hypoblast cells. Here we report formation of human blastocyst models by self-organization solely of naïve pluripotent stem cells. The embryo models comprise the three founding lineages, epiblast, trophoblast and hypoblast, arranged to mimic the natural blastocyst. Single-cell RNA sequencing validated the identity of each cell type. Overall design: Single cells of human E5, E6 and E7 blastocysts and human blastocyst models by self-organization solely of naïve pluripotent stem cells mRNA profiles were generated using Smart-seq2."],"tag":["xref:PubMed:33957081"],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"Human blastocyst model by self-organization of naïve pluripotent stem cells","description":"Human blastocyst model by self-organization of naïve pluripotent stem cells","dates":{"last_updated":"2025-09-24","first_public":"2021-05-10"},"accession":"PRJNA720968","cross_references":{"GEO":["GSE171820"],"taxon":["9606"],"PubMed":["33957081"]}}