ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR142/056/SRR14212156/SRR14212156_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR142/054/SRR14212154/SRR14212154_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR142/054/SRR14212154/SRR14212154_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR142/055/SRR14212155/SRR14212155_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR142/056/SRR14212156/SRR14212156_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR142/055/SRR14212155/SRR14212155_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR142/053/SRR14212153/SRR14212153_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR142/053/SRR14212153/SRR14212153_2.fastq.gzprimaryOK200GenomicsState Key Laboratory of Molecular Oncology, National Cancer Center, Cancer Hospital Chinese Academy of Medical Scienceshttps://www.ebi.ac.uk/ena/browser/view/PRJNA721314Mus musculusOral and esophageal squamous cell carcinomas (SCCs) are associated with high mortality, yet molecular mechanisms underlying these malignancies are largely unknown. We demonstrate that epigenetic silencing of otubain 2 (OTUB2), a previously recognized oncogene, drives SSCs initiation and drug resistance. Overall design: Analyze the differential expression of genes in Otub2- knockout mice transcriptionally.ENAfalseAnalysis of the differential expression of genes in Otub2- knockout miceAnalysis of the differential expression of genes in Otub2- knockout mice2025-09-242022-10-07PRJNA721314GSE17187810090