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However, it is unknown if these two regulatory mechanisms are linked or exert independent effects in normal epithelial physiology and disease states. We have uncovered a new functional relationship between the chromatin remodeler ARID1A and mRNA translation elongation that is involved in cancer initiation and progression. Overall design: Polysome to Subpolysome Profiling and RNASeq of samplesxref:PubMed:37084735ENAhOSA1, Protein Biosynthesis, Cancer of Bladder, Ribosomal Peptide, SMARCF1, cancer of the bladder, Bladder Tumor, Bladder Cancers, BM029, cancer of the urinary bladder, Neoplasms, Urinary Bladder Neoplasm, Smarcf1, Bladder Tumors, Synthesis, Ribosomal Protein, bladder cancer, Tumor, P270, Translation, BAF250a, tumor of the bladder, hELD, Urinary Bladder Cancer, 1110030E03Rik, Protein, Neoplasm, B120, BLC, Bladder Neoplasms, Polysomes, Bladder Neoplasm, cancer of bladder, MRD14, Genetic Translations, Ribosomal Protein Synthesis, C1orf4, Ribosomal, Genetic, Bladder, mRNA Translation, Biosynthesis, mRNA, Ribosomal Protein Biosynthesis, Malignant Tumor of Urinary Bladder, Osa1, OSA1, BAF250, Cancer of the Bladder, Peptide Biosynthesis, Protein Synthesis, Protein Translation, Polyribosome, Polysome., Bladder Cancer, polyribosome, Ribosomal Peptide Biosynthesis, cancer of urinary bladder, Genetic Translation, ELD, mRNA Translations, Urinary Bladder, urinary bladder cancer, Cancer, TumorshOSA1, Protein Biosynthesis, Cancer of Bladder, Ribosomal Peptide, SMARCF1, cancer of the bladder, Bladder Tumor, Bladder Cancers, BM029, cancer of the urinary bladder, Neoplasms, Urinary Bladder Neoplasm, Smarcf1, Bladder Tumors, Synthesis, Ribosomal Protein, bladder cancer, Tumor, P270, Translation, BAF250a, tumor of the bladder, hELD, Urinary Bladder Cancer, 1110030E03Rik, Protein, Neoplasm, B120, BLC, Bladder Neoplasms, Polysomes, Bladder Neoplasm, cancer of bladder, MRD14, Genetic Translations, Ribosomal Protein Synthesis, C1orf4, Ribosomal, Genetic, Bladder, mRNA Translation, Biosynthesis, mRNA, Ribosomal Protein Biosynthesis, Malignant Tumor of Urinary Bladder, Osa1, OSA1, BAF250, Cancer of the Bladder, Peptide Biosynthesis, Protein Synthesis, Protein Translation, Polyribosome, Polysome., Bladder Cancer, polyribosome, Ribosomal Peptide Biosynthesis, cancer of urinary bladder, Genetic Translation, ELD, mRNA Translations, Urinary Bladder, urinary bladder cancer, Cancer, TumorsfalseDissecting the interface between ARID1A and mRNA translation in bladder cancer (Polysome)Dissecting the interface between ARID1A and mRNA translation in bladder cancer (Polysome)2025-09-242023-03-17PRJNA729094GSE1742831009037084735