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Jackson Laboratory for Genomic Medicine"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA736108"],"long_description":["The skin microbiome plays a critical role in skin homeostasis and disorders. UV-radiation is the major cause for nonmelanoma skin cancer, but the microbiome might be an additional, unexplored risk factor and potential disease biomarker. We collected and sequenced skin swabs from patients with actinic keratosis (AK) and squamous cell carcinoma (SCC) as well as healthy control individuals. The idea was to identify microbial biomarkers for cancer-precursor AK and malignant SCC to gain understanding of the potential microbial component contributing to skin carcinogenesis."],"repository":["ENA"],"description_synonyms":["dermis plus epidermis plus hypodermis, the integument, Microbial Community Composition, Community Composition, region of skin, Oct-11a, pelt, Otf-11, Skn-li, malignant neoplasm of skin, Neoplasms, \"malignant neoplasm of skin\" EXACT [MTH:NOCODE], CA - skin cancer, skin zone, \"skin cancer\" EXACT [CSP2005:2020-0536], \"malignant neoplasm of skin NOS (disorder)\" EXACT [SNOMEDCT_2005_07_31:188143008], \"malignant neoplasm of skin, integumental organ, Microbial, Cancer of Skin, epidermis, Human, cancer of skin, skin plus hypodermis, Oct11, skin region, BC033609, Neoplasm, Skin Cancers, Skin-1a, \"melanoma and Non-melanoma skin cancer\" EXACT [NCI2004_11_17:C2920], tegument, Skin, Microbial Communities, integumentum commune, Skn-1a, Microbiome, skin benign neoplasm, \"CA - skin cancer\" EXACT [SNOMEDCT_2005_07_31:363511009], Microbiomes, skin, Microbial Community Compositions, melanoma and Non-melanoma skin cancer., \"malignant neoplasm of skin (disorder)\" EXACT [SNOMEDCT_2005_07_31:372130007], Microbial Community, Microbial Community Structure, vertebrate integument, dermoid system, Community Structure, Skin Cancer, entire skin, Cancers, SKIN, mKIAA0493, Epoc-1, Composition, skin organ, portion of skin, unspecified (disorder)\" EXACT [SNOMEDCT_2005_07_31:190107001], vertebrate epidermis, integument, Fam91a1, Otf11, Microbial Community Structures, Microbiotas, entire integument, Skin Neoplasm, AV220772, dermal system, Cancer of the Skin, skin and subcutaneous tissue, Human Microbiomes, Community, Human Microbiome, Cancer"],"additional_accession":[]},"is_claimable":false,"name":"","description":"The skin microbiome in skin cancer progression","dates":{"last_updated":"2023-05-17","first_public":"2022-05-09"},"accession":"PRJNA736108","cross_references":{}}