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du Thorax, INSERM"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA779393"],"scientific_name":["Mus musculus"],"tag":["xref:PubMed:35021082"],"long_description":["We generated Bscl2lox/lox mice X ERT2-Adipoq-CRE mice, allowing inducible seipin deletion in adipocytes upon tamoxifen addition (iATSKO). Indeed, a 5-day tamoxifen treatment led to a dramatic decrease in Bscl2 mRNA in the adipose tissue. To study the effects of seipin deficiency in vivo on adipose tissue homeostasis in an unbiased manner, we used 3’-signal recognition particle (SRP) RNA sequencing. Overall design: This experiment compare the gene expression of 4 groups of mice (Bscl2lox/lox Bscl2lox/lox -ERT2-Adipoq-CRE Bscl2lox/lox+ tamoxifen Bscl2lox/lox -ERT2-Adipoq-CRE + Tamoxifen that we call iATSKO. We are folowing gene expression over time : 15 days, 30 days, and 90 days after the initiation of tamoxifen injection."],"repository":["ENA"],"description_synonyms":["White Adipose, 3.4.22.-, RNA, RNA Sequence Determination, Laboratory, RNA Sequence Determinations, Sequence Determination, RNA Sequence, Mus domesticus, CASP14, mouse, mini-ICE, CASP-14, Seipin, House Mouse, Determinations, House, Mus, Mini-ICE, Mus musculus domesticus, Analysis, Mice, Mus musculus., Mus musculus, Caspase-14 subunit p10, Analyses, Determination, Swiss, mice, EG:BACR7C10.1, Tissue, Swiss Mouse, House Mice, Swiss Mice, Caspase-14 subunit p19, White Adipose Tissue, White Fat, MICE, Sequence Determinations, Sequencing, CG9904, Laboratory Mice, domesticus, RNA Sequence Analyses, DmelCG9904, RNA Sequence Analysis, RNA Sequencing, White, Mouse, Fat, Laboratory Mouse, textus adiposus albus, Sequence Analyses"],"name_synonyms":["White Adipose, 3.4.22.-, RNA, RNA Sequence Determination, Laboratory, RNA Sequence Determinations, Sequence Determination, RNA Sequence, Mus domesticus, CASP14, mouse, mini-ICE, CASP-14, Seipin, House Mouse, Determinations, House, Mus, Mini-ICE, Mus musculus domesticus, Analysis, Mice, Mus musculus., Mus musculus, Caspase-14 subunit p10, Analyses, Determination, Swiss, mice, EG:BACR7C10.1, Tissue, Swiss Mouse, House Mice, Swiss Mice, Caspase-14 subunit p19, White Adipose Tissue, White Fat, MICE, Sequence Determinations, Sequencing, CG9904, Laboratory Mice, domesticus, RNA Sequence Analyses, DmelCG9904, RNA Sequence Analysis, RNA Sequencing, White, Mouse, Fat, Laboratory Mouse, textus adiposus albus, Sequence Analyses"],"additional_accession":[]},"is_claimable":false,"name":"RNA sequencing of inguinal white adipose tissue from seipin-deficient mice and appropriate controls","description":"RNA sequencing of inguinal white adipose tissue from seipin-deficient mice and appropriate controls","dates":{"last_updated":"2025-09-24","first_public":"2022-01-12"},"accession":"PRJNA779393","cross_references":{"GEO":["GSE188544"],"taxon":["10090"],"PubMed":["35021082"]}}