ENAGenomicsunion hospital, tongji medical college, huazhong university of science and technologyhttps://www.ebi.ac.uk/ena/browser/view/PRJNA805306Homo sapiensMany intrinsic and extrinsic factors involved in 5-Fu resistance in colorectal cancer have been well studied. Here, colorectal cancer organoids were employed for the first time to reveal 5-Fu resistance mechanisms of colorectal cancer. We utilized transcriptome sequencing to dissect 5-Fu resistant molecular characteristics of colorectal cancer organoids.ENAHuman, Modern., human being, Man (Taxonomy), Homo sapiens, man, Man, human, Modern ManColorectal Neoplasm, Carcinoma, Fluorouracil Monopotassium Salt, 5-Fluorouracil, 5 FU Medac, insensitive, Colorectal Cancer, Carac, fluorouracil, Ribofluor, Feature, Neoplasms, 5-Fluoracil, 5-FU Medac, Fluorouracil Monosodium Salt, Tumor, Haemato FU, Onkofluor, autosomal dominant, 5 Fluorouracil Biosyn, Fluorouracil-GRY, Flurodex, 5 Fluorouracil, Colorectal, colorectal cancer, Characteristic, 4-dione, Fluorouracil Mononitrate, Efudix, Neoplasm, Neofluor, 2, 4(1H, Fluoro Uracile ICN, CRC, Colorectal Cancers, Fluoro-Uracile ICN, Fluorouracil Potassium Salt, Colorectal Tumors, Carcinomas, large bowel cancer, 5FU, 5-Fluorouracil-Biosyn, 5-FU Lederle, resistant, Fluorouracilo Ferrer Far, susceptibility to, Colorectal Carcinoma, Efudex, Colorectal Carcinomas, Adrucil, 5 HU Hexal, Cancers, Colorectal Tumor, Features, Fluoruracil, Fluracedyl, Fluorouracile Dakota, Organoid., cancer of large bowel, large intestine cancer, Fluorouracil, Fluorouracile, cancer of the large intestine, Fluoroplex, colon cancer, 5-HU Hexal, 3H)-Pyrimidinedione, fluorouracilum, Haemato-FU, cancer of the large bowel, 5-fluoro-, Fluorouracil GRY, Characteristics, cancer of large intestine, fluorouracilo, 5-Fluoropyrimidine-2, Dakota, somatic mutation, colorectal (colon or rectal) cancer, 5-FU, 5 FU Lederle, Tumors, CancerfalseHomo sapiens5-Fu resistant molecular characteristics of colorectal cancer organoids2025-09-242022-02-13PRJNA8053069606