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Radvanyi, UMR 144, Institut Curiehttps://www.ebi.ac.uk/ena/browser/view/PRJNA808403Mus musculusxref:PubMed:36695554RNA-seq data of microdissected lesions occurring in C57BL/6 male mice treated with N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN) and normal control urothelium from untreated mice. Overall design: RNA-sequencing of 37 microdissected samples, including 29 lesions from 27 BBN-exposed mice representative of all stages of carcinogenesis - hyperplasia (n=4), dysplasia (n=5), CIS (n=3), pTa (n=5), pT1 (n=7), MIBC (n=5) - as well as 3 BBN-exposed urothelia of normal morphology (adjacent to hyperplasia) and 5 unexposed control urothelia.ENAfalseMulti-stage expression in BBN mouse model reveals progression-associated molecular changes in basal/squamous and sarcomatoid bladder carcinogenesisMulti-stage expression in BBN mouse model reveals progression-associated molecular changes in basal/squamous and sarcomatoid bladder carcinogenesis2025-09-242023-01-27PRJNA808403GSE1970161009036695554