ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR184/054/SRR18453054/SRR18453054.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR184/044/SRR18453044/SRR18453044.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR184/048/SRR18453048/SRR18453048.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR184/055/SRR18453055/SRR18453055.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR184/053/SRR18453053/SRR18453053.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR184/045/SRR18453045/SRR18453045.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR184/049/SRR18453049/SRR18453049.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR184/052/SRR18453052/SRR18453052.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR184/051/SRR18453051/SRR18453051.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR184/047/SRR18453047/SRR18453047.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR184/046/SRR18453046/SRR18453046.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR184/050/SRR18453050/SRR18453050.fastq.gzprimaryOK200GenomicsBioengineering, University of Washingtonhttps://www.ebi.ac.uk/ena/browser/view/PRJNA819019Homo sapiensxref:PubMed:36003954We report the transcriptomic differences between engineered heart tissues generated from hiPSCs with a dystrophin-truncating mutation and an isogenic control. We find that the dystrophin mutation induces profound differences at the transcriptomic level and illuminates potential disease-causing mechanisms. Overall design: RNA sequencing of control and dystrophic engineered heart tissuesENAfalseRNA sequencing of control and dystrophin-mutant engineered heart tissues from human induced pluripotent stem cell-derived cardiomyocytesRNA sequencing of control and dystrophin-mutant engineered heart tissues from human induced pluripotent stem cell-derived cardiomyocytes2025-09-242022-10-07PRJNA819019GSE199242960636003954