ENAGenomicsIMCE, Kyushu Universityhttps://www.ebi.ac.uk/ena/browser/view/PRJNA821087Homo sapiensTo reveal the comprehensive gene expression of normal human dermal fibroblasts (NHDFs) based on the interaction of GlcNAc-bearing polymer, AC-GlcNAc10, with cell surface vimentin at 24 h, we performed a DNA microarray for NHDFs treated with AC-GlcNAc10. The DNA microarray analysis revealed altered expression of approximately 1000 genes in NHDF vs. NHDF treated with AC-GlcNAc10 by extracting differentially expressed genes with the ratio of >1.5 and 2.0 and <-2.0. We observed the downregulation of gene expression related to cell cycle progression, such as baculoviral IAP repeat-containing protein 5 (BIRC5 survivin), and the upregulation of gene expression related to cell cycle arrest, such as cyclin-dependent kinase inhibitor 1A (CDKN1A p21). Overall design: NHDFs are control. The data showed comparison between NHDFs (control) and AC-GlcNAc10-treated NHDFsxref:PubMed:36190502ENApolymer, macromolecules, average, Glucosamine, N-Acetyl, D-Glucose, N-Acetylglucosamine, N-Acetyl Glucosamine, human being, Gene Expressions, Man (Taxonomy), polymer molecule, N-acetylglucosamines, Acetyl, determination, N Acetyl D Glucosamine, Modern, N-Acetyl-beta-D-Glucosamine, Gene, 2-(acetylamino)-2-deoxy-, Expressions, man, 2 Acetamido 2 Deoxyglucose, human, Human, N-Acetyl-D-Glucosamine, Acetyl Glucosamine, N Acetyl beta D Glucosamine, Homo sapiens, Polymer, Modern Man, 2 Acetamido 2 Deoxy D Glucose, N Acetyl Glucosamine, chemical analysis, 2-Acetamido-2-Deoxy-D-Glucose, N Acetylglucosamine, 2-Acetamido-2-Deoxyglucose, beta-N-Acetylglucosamine, assay, Expression, polymers., macromolecule, Man, Fibroblast, beta N Acetylglucosaminepolymer, macromolecules, average, Glucosamine, N-Acetyl, D-Glucose, N-Acetylglucosamine, N-Acetyl Glucosamine, human being, Gene Expressions, Man (Taxonomy), polymer molecule, N-acetylglucosamines, Acetyl, determination, N Acetyl D Glucosamine, Modern, N-Acetyl-beta-D-Glucosamine, Gene, 2-(acetylamino)-2-deoxy-, Expressions, man, 2 Acetamido 2 Deoxyglucose, human, Human, N-Acetyl-D-Glucosamine, Acetyl Glucosamine, N Acetyl beta D Glucosamine, Homo sapiens, Polymer, Modern Man, 2 Acetamido 2 Deoxy D Glucose, N Acetyl Glucosamine, chemical analysis, 2-Acetamido-2-Deoxy-D-Glucose, N Acetylglucosamine, 2-Acetamido-2-Deoxyglucose, beta-N-Acetylglucosamine, assay, Expression, polymers., macromolecule, Man, Fibroblast, beta N AcetylglucosaminefalseComprehensive analysis for gene expressions of normal human dermal fibroblasts supplemented with N-acetylglucosamine -bearing polymersComprehensive analysis for gene expressions of normal human dermal fibroblasts supplemented with N-acetylglucosamine -bearing polymers2025-09-242022-04-01PRJNA821087GSE199655960636190502