ENAapplication/xmlftp://primary200OKGenomicsSiwei Fenghttps://www.ebi.ac.uk/ena/browser/view/PRJNA831569Mus musculusWe found that several autophagy genes in myeloid cells are required to protect against high-dose Mtb (~1000cfu) infection. To understand the immune cell population in these mice after high-dose Mtb infection and what may contribute to the susceptibility, we did scRNAseq on naïve mice and mice infected with high-dose of Mtb strain Erdman. Overall design: Lung cells from naive Atg14f/f,Atg14f/f-CD11c-cre, Atg14f/f-LysM-cre and 21dpi Atg14f/f,Atg14f/f-CD11c-cre, Atg14f/f-LysM-cre mice. Cells pooled from 4 mice each, age 8-10 wks.ENALyzs, 3.4.22.-, Lzp, Cr4, pulmo, Laboratory, CD11c, AI449405, AI326280, Mus domesticus, CASP14, mouse, scRNA-seq, lung parenchyma, mini-ICE, CASP-14, ITGAX, 95, House Mouse, Cell, single cell RNA sequencing, single-cell transcriptome sequencing, single-cell RNA-seq, House, Mus, parenchyma of lung, Mini-ICE, lung, Mus musculus domesticus, Lzm-s1, neoplasm, Mice, 95 alpha chain, neoplasms, Mus musculus., Mus musculus, Caspase-14 subunit p10, Swiss, mice, Swiss Mouse, Leukocyte adhesion glycoprotein p150, House Mice, Swiss Mice, Caspase-14 subunit p19, Leu M5, MICE, leukocyte adhesion glycoprotein p150, Laboratory Mice, domesticus, Lysm, Lys, pulmonary, N418, CD11 antigen-like family member C, leukocyte adhesion receptor p150, CD11C, Leukocyte adhesion receptor p150, Lungs, Mouse, SLEB6, Laboratory Mouse, Cd11c, LzmLyzs, 3.4.22.-, Lzp, Cr4, pulmo, Laboratory, CD11c, AI449405, AI326280, Mus domesticus, CASP14, mouse, scRNA-seq, lung parenchyma, mini-ICE, CASP-14, ITGAX, 95, House Mouse, Cell, single cell RNA sequencing, single-cell transcriptome sequencing, single-cell RNA-seq, House, Mus, parenchyma of lung, Mini-ICE, lung, Mus musculus domesticus, Lzm-s1, neoplasm, Mice, 95 alpha chain, neoplasms, Mus musculus., Mus musculus, Caspase-14 subunit p10, Swiss, mice, Swiss Mouse, Leukocyte adhesion glycoprotein p150, House Mice, Swiss Mice, Caspase-14 subunit p19, Leu M5, MICE, leukocyte adhesion glycoprotein p150, Laboratory Mice, domesticus, Lysm, Lys, pulmonary, N418, CD11 antigen-like family member C, leukocyte adhesion receptor p150, CD11C, Leukocyte adhesion receptor p150, Lungs, Mouse, SLEB6, Laboratory Mouse, Cd11c, LzmfalseSingle-cell RNA sequencing of total lung cells from Atg14f/f,Atg14f/f-CD11c-cre, Atg14f/f-LysM-cre miceSingle-cell RNA sequencing of total lung cells from Atg14f/f,Atg14f/f-CD11c-cre, Atg14f/f-LysM-cre mice2025-09-242022-04-26PRJNA831569GSE20141010090