ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/021/SRR19264421/SRR19264421_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/009/SRR19264409/SRR19264409_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/013/SRR19264413/SRR19264413_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/017/SRR19264417/SRR19264417_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/016/SRR19264416/SRR19264416_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/011/SRR19264411/SRR19264411_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/020/SRR19264420/SRR19264420_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/008/SRR19264408/SRR19264408_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/018/SRR19264418/SRR19264418_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/012/SRR19264412/SRR19264412_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/014/SRR19264414/SRR19264414_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/020/SRR19264420/SRR19264420_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/019/SRR19264419/SRR19264419_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/008/SRR19264408/SRR19264408_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/010/SRR19264410/SRR19264410_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/013/SRR19264413/SRR19264413_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/022/SRR19264422/SRR19264422_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/011/SRR19264411/SRR19264411_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/018/SRR19264418/SRR19264418_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/019/SRR19264419/SRR19264419_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/015/SRR19264415/SRR19264415_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/014/SRR19264414/SRR19264414_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/017/SRR19264417/SRR19264417_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/016/SRR19264416/SRR19264416_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/010/SRR19264410/SRR19264410_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/022/SRR19264422/SRR19264422_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/021/SRR19264421/SRR19264421_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/012/SRR19264412/SRR19264412_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/015/SRR19264415/SRR19264415_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR192/009/SRR19264409/SRR19264409_1.fastq.gzprimaryOK200GenomicsComprehensive Pathology, Tokyo Medical and Dental Universityhttps://www.ebi.ac.uk/ena/browser/view/PRJNA839264Homo sapiensxref:PubMed:37264057The inductional abilities of drug resistance by the knockout of C9orf89, MAGI2, MLPH, or RHBDD2 in supporting cells were solidly confirmed by the reduction of apoptosis by cell-cell interactions. Overall design: HEK293T clones of C9orf89-CRISPR-KO, C19orf70-CRISPR-KO, C21orf33-CRISPR-KO, MAGI2-CRISPR-KO, MLPH-CRISPR-KO, and RHBDD2-CRISPR-KO were established with the limiting dilution methods and conducted in the following co-culture experiment.ENAfalseThe key factors of drug resistance with cell-cell interactionsThe key factors of drug resistance with cell-cell interactions2025-09-242022-07-14PRJNA839264GSE203256960637264057