{"database":"ENA","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Fastqsanger.gz":["ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR195/066/SRR19577166/SRR19577166_2.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR195/065/SRR19577165/SRR19577165_2.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR195/065/SRR19577165/SRR19577165_1.fastq.gz","ftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR195/066/SRR19577166/SRR19577166_1.fastq.gz"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"center_name":["National cheng kung university hospital"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA846951"],"long_description":["One case exhibited MSI-H but no loss in the dMMR IHC. Results of the NGS analysis in this case showed that, as compared with the non-tumorous region, the CRC tumour specimen harbored three major somatic mutations: 15% alleles with MLH1 c.2040C>T silent mutation, 31% with PMS2 c.379G>A, which results in missense mutation Ala127Thr, and 40% with MSH6 c.3152delT mutation, which results in frameshift at Val1051 and premature translation termination."],"repository":["ENA"],"additional_accession":[]},"is_claimable":false,"name":"","description":"MSH6 sequence","dates":{"last_updated":"2023-05-19","first_public":"2022-06-16"},"accession":"PRJNA846951","cross_references":{}}