ENAapplication/xmlftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR220/035/SRR22028435/SRR22028435_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR220/034/SRR22028434/SRR22028434_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR220/033/SRR22028433/SRR22028433_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR220/030/SRR22028430/SRR22028430_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR220/030/SRR22028430/SRR22028430_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR220/033/SRR22028433/SRR22028433_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR220/032/SRR22028432/SRR22028432_1.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR220/035/SRR22028435/SRR22028435_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR220/034/SRR22028434/SRR22028434_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR220/031/SRR22028431/SRR22028431_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR220/032/SRR22028432/SRR22028432_2.fastq.gzftp://ftp.sra.ebi.ac.uk/vol1/fastq/SRR220/031/SRR22028431/SRR22028431_1.fastq.gzprimaryOK200GenomicsQu lab, Pediatrics, Emory Universityhttps://www.ebi.ac.uk/ena/browser/view/PRJNA894154Mus musculusTo understand the function of PTPMT1 in CD8 T cells responses, we characterized the transcriptomes of activated CD8+ T cells from PTPMT1 wildtype and knockout mice Overall design: CD8 T cells from PTPMT1 wildtype and knockout mice were isolated from spleen and lymph nodes. The purified CD8 T cells were activated by CD3/CD28 antibodies-coupled Dynabeads for 3 days in vitro, then the activated CD8 T cells were used for comparative gene expression profiling analysis by RNA-seq.xref:PubMed:38055827ENAfalsePTPMT1 is critical for both expansion and differentiation of activated CD8 T cellsPTPMT1 is critical for both expansion and differentiation of activated CD8 T cells2025-09-242023-11-23PRJNA894154GSE2165231009038055827