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Wang, 4DCP, Janelia Research Campus"],"full_dataset_link":["https://www.ebi.ac.uk/ena/browser/view/PRJNA952585"],"scientific_name":["Caenorhabditis elegans"],"long_description":["We presents a complete single-cell atlas of aging worms, encompassing both somatic and germ cell types. This atlas was built upon 241K nuclei across the worm lifespan at day 1, 6, 12, and 14 (100%, 99%, 61%, and 14% survival rates, respectively). The worms were aged under normal physiological conditions, without interfering with their reproductive processes. Overall design: To perfom snRNAseq for wild-type and longevity worms, we harvested and homogenized ~2,000 worms for each genotype/condition. Nuclei were isolated using fluorescence-activated cell sorting (FACS) based on the DNA content signal and then proceed with 10x Chromium sequcing."],"tag":["xref:PubMed:38816550"],"repository":["ENA"],"description_synonyms":["nuclei, nucleus atomi, Life Span, length of life, lifespan, noyau atomique, Transcriptome, Lifespans, Life Spans, Transcriptome Profile, entire lifespan, entire life cycle, nucleo, noyau, Profile, adult stage, Length of Life, Expression Profiles, life., Gene Expression Profile, Gene, Kern, Profiles, Atomkern, Signatures, Gene Expression, nucleus, Expression Signature, Gene Expression Profiles, Expression Signatures, Gene Expression Signatures, Transcriptomes, Gene Expression Signature, Signature, nucleo atomico, Expression Profile, Adults, adult, Lifespan, Transcriptome Profiles"],"name_synonyms":["nuclei, nucleus atomi, Life Span, length of life, lifespan, noyau atomique, Transcriptome, Lifespans, Life Spans, Transcriptome Profile, entire lifespan, entire life cycle, nucleo, noyau, Profile, adult stage, Length of Life, Expression Profiles, life., Gene Expression Profile, Gene, Kern, Profiles, Atomkern, Signatures, Gene Expression, nucleus, Expression Signature, Gene Expression Profiles, Expression Signatures, Gene Expression Signatures, Transcriptomes, Gene Expression Signature, Signature, nucleo atomico, Expression Profile, Adults, adult, Lifespan, Transcriptome Profiles"],"additional_accession":[]},"is_claimable":false,"name":"Single nuclei gene expression profile for adult C. elegans and several longevity mutants","description":"Single nuclei gene expression profile for adult C. elegans and several longevity mutants","dates":{"last_updated":"2025-09-24","first_public":"2024-03-30"},"accession":"PRJNA952585","cross_references":{"GEO":["GSE229022"],"taxon":["6239"],"PubMed":["38816550"]}}