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Puniya2021 - CD4+ Th1 cell metabolic model

ABSTRACT: CD4+ T cells are critical components in the human immune system. They produce cytokines to fight against pathogens and abnormal cells and stimulate other cells, such as B cells, macrophages, and neutrophils, to generate an immune response. T helper 1 (Th1) cells are subtypes of CD4+ T cells that differentiate from naive CD4+ T cells in a specific cytokine environment. The Th1 cell model consists of 3956 reactions, 2517 metabolites, and 1133 genes. CD4+ T cell models helped identify drug targets and repurposable drugs against autoimmune diseases.

SUBMITTER: Bhanwar Lal Puniya

PROVIDER: MODEL1909260004 | BioModels | 2022-06-14

REPOSITORIES: BioModels

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| EGAS00001001456 | EGA

Expression data for effector T cells

2012-05-13 | GSE32901 | GEO

CD4+ cell transcriptional profiling by RNA sequencing

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| phs000626 | dbGaP

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