Ontology highlight
ABSTRACT:
SUBMITTER: de la Cruz NB
PROVIDER: S-EPMC2206703 | biostudies-literature | 2007 Jul
REPOSITORIES: biostudies-literature
de la Cruz Norberto B NB Peterson Francis C FC Lytle Betsy L BL Volkman Brian F BF
Protein science : a publication of the Protein Society 20070613 7
The protein Bc059385, whose solution structure is reported here, is the human representative of a recently identified family of membrane-anchored ubiquitin-fold (MUB) proteins. Analysis of their similarity to ubiquitin indicates that homologous amino acid residues in MUBs form a hydrophobic surface very similar to the recognition patch surrounding Ile-44 in ubiquitin. This suggests that MUBs may interact with proteins containing an alpha-helical motif similar to those of some ubiquitin binding d ...[more]