Ontology highlight
ABSTRACT:
SUBMITTER: Manjasetty BA
PROVIDER: S-EPMC2242484 | biostudies-literature | 2006 Apr
REPOSITORIES: biostudies-literature
Protein science : a publication of the Protein Society 20060307 4
The human protein PTD012 is the longer product of an alternatively spliced gene and was described to be localized in the nucleus. The X-ray structure analysis at 1.7 A resolution of PTD012 through SAD phasing reveals a monomeric protein and a novel fold. The shorter splice form was also studied and appears to be unfolded and non-functional. The structure of PTD012 displays an alphabetabetaalpha four-layer topology. A metal ion residing between the central beta-sheets is partially coordinated by ...[more]