Transcriptomics

Dataset Information

3

Transcription profiling of Streptococcus pneumoniae wild type and Rgg mutants in aerobic and anaerobic conditions


ABSTRACT: Data is also available from http://bugs.sgul.ac.uk/E-BUGS-70

SUBMITTER: BuG@S group  

PROVIDER: E-BUGS-70 | ArrayExpress | 2009-10-12

REPOSITORIES: ArrayExpress

Dataset's files

Source:
Action DRS
E-BUGS-70.2columns.txt Txt
E-BUGS-70.2columns.xls Xls
E-BUGS-70.README.txt Txt
E-BUGS-70.biosamples.map Other
E-BUGS-70.biosamples.png Other
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Publications

The pneumococcal response to oxidative stress includes a role for Rgg.

Bortoni Magda E ME   Terra Vanessa S VS   Hinds Jason J   Andrew Peter W PW   Yesilkaya Hasan H  

Microbiology (Reading, England) 20090917 Pt 12


Streptococcus pneumoniae resides in the oxygen-rich environment of the upper respiratory tract, and therefore the ability to survive in the presence of oxygen is an important aspect of its in vivo survival. To investigate how S. pneumoniae adapts to oxygen, we determined the global gene expression profile of the micro-organism in aerobiosis and anaerobiosis. It was found that exposure to aerobiosis elevated the expression of 54 genes, while the expression of 15 genes was downregulated. Notably t  ...[more]

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