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The purpose is to determine the role of TLR3-/- on the regulation of the host immune response during lethal SARS-CoV infection Groups of 10 week old C57BL6/NJ or TLR3-/- mice were infected with MA15...
ORGANISM(S):Mus musculus 
2015-05-22 | E-GEOD-68820 | ArrayExpress
Early immature T-cell acute lymphoblastic leukemias (T-ALLs) account for about 5-10% of pediatric T-ALLs and are associated with poor prognosis. However, the genetic defects that drive the biology of ...
ORGANISM(S):Homo sapiens 
2014-06-03 | E-GEOD-48046 | ArrayExpress
Primary productivity of open ocean environments, such as those inhabited by marine picocyanobacteria Synechococcus sp.WH8102, are often limited by low inorganic phosphate (P). To observe how this orga...
ORGANISM(S):Synechococcus sp. WH 8102 
2014-05-04 | E-GEOD-13170 | ArrayExpress
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S):Mus musculus 
2015-02-07 | E-GEOD-62664 | ArrayExpress
Embryonic stem cell (ESC) self-renewal and differentiation is governed by a comprehensive regulatory network. Although the transcriptional regulation has been extensively investigated, post-transcript...
ORGANISM(S):Mus musculus 
2014-06-03 | E-GEOD-48436 | ArrayExpress
Follicle assembly is the process by which groups or ‘nests’ of oocytes break down to form primordial follicles. The size of the primordial follicle pool is the major determinant of the reproductive l...
ORGANISM(S):Rattus norvegicus 
2012-03-27 | E-GEOD-8238 | ArrayExpress
Parkinson's disease (PD) is defined by the degeneration of nigral dopaminergic (DA) neurons and can be caused by monogenic mutations of genes such as parkin. The lack of phenotype in parkin knockout m...
ORGANISM(S):Homo sapiens 
2014-05-04 | E-GEOD-35190 | ArrayExpress
P granules in C. elegans are required for fertility and function to maintain germ cell identity and pluripotency.  Sterility in the absence of P granules is often accompanied by the mis-expression of ...
ORGANISM(S):Caenorhabditis elegans 
2015-08-19 | E-GEOD-67954 | ArrayExpress
The adult stem cell marker Lgr5 and its close relative Lgr4 are often co-expressed in Wnt-driven proliferative compartments. Conditional deletion of the two genes in the gut impairs expression of Wnt ...
ORGANISM(S):Mus musculus 
2014-05-02 | E-GEOD-28265 | ArrayExpress
To clarify aberrantly expressed miRNAs affecting the biology of GIST, miRNA array was performed in 19 cases of GIST. A series of 19 GISTs specimens were analyzed using 3D-Gene Human miRNA Oligo chips ...
ORGANISM(S):Homo sapiens 
2014-06-02 | E-GEOD-36087 | ArrayExpress
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