Transcriptomics

Dataset Information

65

RNA-seq of human melanoma samples


ABSTRACT: In this study, mutations present in a series of human melanomas (stage IV disease) will be determined, using autologous blood cells to obtain a reference genome. From each of the samples that are analyzed, tumour-infiltrating T lymphocytes have also been isolated. This offers a unique opportunity to determine which (fraction of) mutations in human cancer leads to epitopes that are recognized by T cells. The resulting information is likely to be of value to understand how T cell activating drugs exert their action.

INSTRUMENT(S): Illumina HiSeq 2000

ORGANISM(S): Homo sapiens  

SUBMITTER: The Wellcome Trust Sanger Institute  

PROVIDER: E-ERAD-61 | ArrayExpress | 2013-01-22

SECONDARY ACCESSION(S): EGAS00001000251

REPOSITORIES: ArrayExpress

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