Transcriptomics

Dataset Information

200

Transcription profiling by array of Mus musculus tissues - GNF Mouse GeneAtlas V3


ABSTRACT: Monocytes and macrophages express an extensive repertoire of G Protein-Coupled Receptors (GPCRs) that regulate inflammation and immunity. In this study we performed a systematic microarray analysis of GPCR expression in primary mouse tissues to identify family members that are either enriched in macrophages compared to a panel of other cell types, or are regulated by an inflammatory stimulus, the bacterial product lipopolysaccharide (LPS). Experiment Overall Design: Multiple tissues were taken from naïve male C57BL6 mice for hybridization to MOE430_2 arrays

INSTRUMENT(S): 418 [Affymetrix]

ORGANISM(S): Mus musculus  

SUBMITTER: John R. Walker  

PROVIDER: E-GEOD-10246 | ArrayExpress | 2008-06-11

SECONDARY ACCESSION(S): GSE10246PRJNA108431

REPOSITORIES: GEO, ArrayExpress

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Publications


BACKGROUND: Monocytes and macrophages express an extensive repertoire of G Protein-Coupled Receptors (GPCRs) that regulate inflammation and immunity. In this study we performed a systematic micro-array analysis of GPCR expression in primary mouse macrophages to identify family members that are either enriched in macrophages compared to a panel of other cell types, or are regulated by an inflammatory stimulus, the bacterial product lipopolysaccharide (LPS). RESULTS: Several members of the P2RY fa  ...[more]

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