Transcriptomics

Dataset Information

2

Liver gene expression profiling of lipoprotein lipase heterozygous knockout mice


ABSTRACT: Lipoprotein lipase (Lpl) was predicted as a causal gene for abdominal using a novel statistical method named LCMS (Schadt et al., 2005, Nature Genetics). In order to validate this prediction, we profiled the liver tissues of lipoprotein lipase heterozygous knockout mice (Lpl+/-) and their littermate wild-type (wt) controls to examine the gene expression signature as well as pathways/networks resulting from the single gene perturbation. 8 Lpl+/- mice and 8 wt controls were profiled. Reference pool included RNA extracted from the liver of 9 wt control mice. Dye-swap was involved in the profiling.

ORGANISM(S): Mus musculus  

SUBMITTER: Xia Yang  

PROVIDER: E-GEOD-11991 | ArrayExpress | 2009-03-07

SECONDARY ACCESSION(S): GSE11991PRJNA109261

REPOSITORIES: GEO, ArrayExpress

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