Dataset Information


Transcriptome analysis of infection of the archaeon Sulfolobus solfataricus with STIV

ABSTRACT: Time series of infection of Sulfolobus solfataricus strain 2-2-12 cells infected with STIV are compared with uninfected cells over 32 h. Two-condition experiment, Control vs. Infected cells sampled at 5 time points (0, 8, 16, 24, 32 h post infection). Biological replicates: 3 control, 3 infected, paired samples independently grown. One replicate per array. Dye swaps.

ORGANISM(S): Saccharolobus solfataricus  

SUBMITTER: Alice C Ortmann   Harmen J vandeWerken  Susan K Brumfield  Mark J Young  Kathleen McInnerney  Kate McInnerney  Jasper Walther  Stan J Broun  Trevor Douglas  Brian Bothner  John vanderOost 

PROVIDER: E-GEOD-12235 | ArrayExpress | 2008-07-25



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Transcriptome analysis of infection of the archaeon Sulfolobus solfataricus with Sulfolobus turreted icosahedral virus.

Ortmann Alice C AC   Brumfield Susan K SK   Walther Jasper J   McInnerney Kathleen K   Brouns Stan J J SJ   van de Werken Harmen J G HJ   Bothner Brian B   Douglas Trevor T   van de Oost John J   Young Mark J MJ  

Journal of Virology 20080312 10

Microarray analysis of infection by Sulfolobus turreted icosahedral virus (STIV) revealed insights into the timing and extent of virus transcription, as well as differential regulation of host genes. Using a microarray containing genes from both the host and the virus, the infection cycle of STIV was studied. Following infection of Sulfolobus solfataricus strain 2-2-12 with STIV, transcription of virus genes was first detected at 8 h postinfection (p.i.), with a peak at 24 h p.i. Lysis of cells  ...[more]

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