ORGANISM(S): Halobacterium salinarum NRC-1
SUBMITTER: Koide Tie Schmid Amy Pan Min Amy K Schmid Baliga Nitin S.
REPOSITORIES: GEO, ArrayExpress
Molecular Systems Biology 20090616
During evolution, enzyme-coding genes are acquired and/or replaced through lateral gene transfer and compiled into metabolic pathways. Gene regulatory networks evolve to fine tune biochemical fluxes through such metabolic pathways, enabling organisms to acclimate to nutrient fluctuations in a competitive environment. Here, we demonstrate that a single TrmB family transcription factor in Halobacterium salinarum NRC-1 globally coordinates functionally linked enzymes of diverse phylogeny in respons ...[more]