Transcriptomics

Dataset Information

36

Transcription profiling of brown adipose tissue from KRAP deficient animals


ABSTRACT: KRAP (Ki-ras-induced actin-interacting protein) is a cytoskeleton-associated protein and a ubiquitous protein among tissues, originally identified as a cancer-related molecule. KRAP-deficient (KRAP-/-) mice show enhanced metabolic rate, decreased adiposity, improved glucose tolerance, hypoinsulinemia and hypoleptinemia. KRAP-/- mice are also protected against high-fat diet-induced obesity and insulin resistance despite of hyperphagia. Experiment Overall Design: Total RNA was extracted from BAT of three pairs of littermates (KO1 vs. WT1, KO2 vs. WT2 and KO3 vs. WT3) fed normal chow.

ORGANISM(S): Mus musculus  

SUBMITTER: takahiro fujimoto   

PROVIDER: E-GEOD-13582 | ArrayExpress| 2011-06-10

SECONDARY ACCESSION(S): GSE13582PRJNA113935

REPOSITORIES: GEO, ArrayExpress

altmetric image

Publications

Sorry, this publication's infomation has not been loaded in the Indexer, please go directly to PUBMED or Altmetric.

Similar Datasets

2009-01-22 | GSE13582 | GEO
2009-01-22 | GSE13583 | GEO
2014-05-01 | E-GEOD-13583 | ArrayExpress
2010-11-26 | GSE24451 | GEO
2012-03-27 | E-GEOD-24451 | ArrayExpress
2012-03-27 | E-GEOD-13585 | ArrayExpress
2014-05-13 | E-GEOD-29541 | ArrayExpress
2009-01-22 | GSE13585 | GEO
2018-07-12 | PXD008599 | Pride
| GSE83684 | GEO